المؤلفون: Daniel C Farley, Laura McCloskey, Barbara A Thorne, Semih U Tareen, Christopher J Nicolai, David J Campbell, Richard Bannister, Hannah J Stewart, Laura JE Pearson, Bentley J Moyer, Scott H Robbins, Leah Zielinski, Tae Kim, Pippa A Radcliffe, Kyriacos A Mitrophanous, Wayne R Gombotz, James E Miskin, Brenna Kelley-Clarke

المصدر: Molecular Therapy: Methods & Clinical Development, Vol 2, Iss , Pp - (2015)

مصطلحات موضوعية: Genetics, QH426-470, Cytology, QH573-671

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2329050116300298; https://doaj.org/toc/2329-0501

URL الوصول: https://doaj.org/article/7f7c5943dd9b4748b580d44545f0e674

المؤلفون: Philip C. Buttery, Richard Harrop, Helene Lepetit, Claire Thiriez, Xavier Drouot, G. Scott Ralph, Jean Pascal Lefaucheur, Cherry Lucas, Philippe Le Corvoisier, Pippa A Radcliffe, Philippe Hantraye, Patrice Dolphin, Pierre Brugières, Hirokazu Iwamuro, Sarah L Mason, Olivier Rascol, Gilles Fénelon, David P. Breen, Inanna Gabriel, Sarah Deeley, Michelle Kelleher, Sonia Lavisse, Kou Abhay, Aurélie Kas, Stuart Naylor, Roger A. Barker, Jean Marc Gurruchaga, Pierre Cesaro, Natalie Valle Guzman, Stéphane Palfi, Colin Watts, Kyriacos A. Mitrophanous, Nicholas D. Mazarakis, Bijan Ghaleh, James Miskin, Philippe Remy, Naoki Tani, Susan M. Kingsman

المصدر: The Lancet. 383:1138-1146

مصطلحات موضوعية: Male, medicine.medical_specialty, Parkinson's disease, Tyrosine 3-Monooxygenase, Dopamine, Genetic Vectors, Injections, Intralesional, ProSavin, Transfection, Antiparkinson Agents, Internal medicine, Humans, Medicine, Transgenes, GTP Cyclohydrolase, Adverse effect, Aged, business.industry, Dopaminergic Neurons, Putamen, Dopaminergic, Parkinson Disease, Genetic Therapy, General Medicine, Middle Aged, medicine.disease, Surgery, Clinical trial, Tolerability, Dopa Decarboxylase, business, Follow-Up Studies, Infectious Anemia Virus, Equine, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc0a5babde8323ced726571ab8e4abb8
https://doi.org/10.1016/s0140-6736(13)61939-x

المؤلفون: Liang Fong-Wong, G. Scott Ralph, Vinay Thoree, Michelle Kelleher, Iain T. Strickland, Kyriacos A. Mitrophanous, Hannah J Stewart, Pippa A Radcliffe, Laura Stevenson, Janine McCarthy, Daniel Chipchase

المصدر: Human Gene Therapy. 22:357-369

مصطلحات موضوعية: Male, Transcription, Genetic, Genetic enhancement, Genetic Vectors, Cell, Gene Dosage, Computational biology, Biology, Gene dosage, Genomic Instability, Cell Line, Viral vector, Equine infectious anemia, Industrial Microbiology, Transduction (genetics), Transduction, Genetic, Genetics, medicine, Animals, Humans, Transgenes, Vector (molecular biology), Rats, Wistar, Molecular Biology, HEK 293 cells, Brain, Parkinson Disease, Genetic Therapy, biology.organism_classification, Rats, HEK293 Cells, medicine.anatomical_structure, Immunology, Molecular Medicine, Infectious Anemia Virus, Equine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abbd4ab341a8a3e3de57397f33187d55
https://doi.org/10.1089/hum.2010.142

المؤلفون: C. D. Robertson, Kyriacos A. Mitrophanous, Jacqueline Smith, Adrian Sherman, Michael J. McGrew, P. Barnard, E. A. Elliot, Helen Sang, Pippa A Radcliffe, Simon G. Lillico, C. Haslam

المصدر: Lillico, S G, Sherman, A, McGrew, M J, Robertson, C D, Smith, J, Haslam, C, Barnard, P, Radcliffe, P A, Mitrophanous, K A, Elliot, E A & Sang, H M 2007, ' Oviduct-specific expression of two therapeutic proteins in transgenic hens ', Proceedings of the National Academy of Sciences, vol. 104, no. 6, pp. 1771-6 . https://doi.org/10.1073/pnas.0610401104

مصطلحات موضوعية: Male, Eggs, Transgene, Genetic Vectors, Egg protein, Oviducts, Animals, Genetically Modified, Mice, Egg White, medicine, Animals, Humans, Gene silencing, Ovum, Multidisciplinary, biology, Lentivirus, Egg Proteins, Gene Transfer Techniques, Interferon beta-1a, Interferon-beta, Biological Sciences, Molecular biology, Recombinant Proteins, Cell biology, Transgenesis, Ovalbumin, biology.protein, Oviduct, Female, Chickens, Infectious Anemia Virus, Equine, medicine.drug, Egg white

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c09b1e3442649e4021cb3b883e3d357f
https://doi.org/10.1073/pnas.0610401104

المؤلفون: Dai Hirata, Leah A. Vardy, Pippa A. Radcliffe, Takashi Toda

المصدر: Molecular Biology of the Cell. 10:2987-3001

مصطلحات موضوعية: Cytoplasm, Microtubule-associated protein, Genes, Fungal, Molecular Sequence Data, Mutant, Gene Dosage, Glycine, Microtubules, Article, Cofactor, Fungal Proteins, Suppression, Genetic, Tubulin, Microtubule, Schizosaccharomyces, Amino Acid Sequence, Molecular Biology, Genes, Essential, Sequence Homology, Amino Acid, biology, Genetic Complementation Test, Temperature, Cell Polarity, Cell Biology, biology.organism_classification, Yeast, Neoplasm Proteins, Molecular Weight, Biochemistry, Mutation, biology.protein, Schizosaccharomyces pombe Proteins, Microtubule-Associated Proteins, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9838a12672dd7f2728ff9bebce538a79
https://doi.org/10.1091/mbc.10.9.2987

المؤلفون: Pippa A Radcliffe, K A Mitrophanous, M A Leroux-Carlucci, C J M Sion, Hannah J Stewart

المصدر: Gene therapy. 16(6)

مصطلحات موضوعية: viruses, Genetic enhancement, Blotting, Western, Genetic Vectors, Cell Culture Techniques, Biology, Transfection, Virus Replication, Genomic Instability, Viral vector, Cell Line, chemistry.chemical_compound, Open Reading Frames, Viral Envelope Proteins, Genetics, Animals, TetR, Molecular Biology, Gene, Membrane Glycoproteins, Virus Assembly, Lentivirus, RNA-Directed DNA Polymerase, Genetic Therapy, biology.organism_classification, Virology, Anti-Bacterial Agents, Clone Cells, Fusion Proteins, gag-pol, Repressor Proteins, chemistry, Viral replication, Gene Expression Regulation, Vesicular stomatitis virus, Doxycycline, Molecular Medicine, Infectious Anemia Virus, Equine, Plasmids

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4234d2b7b71ba1be231f30b9bf91b3f
https://pubmed.ncbi.nlm.nih.gov/19262613

المؤلفون: Noemí Cambray, Michael J. McGrew, Valerie Wilson, Simon G. Lillico, Adrian Sherman, Hazel Gilhooley, F M Ellard, Kyriacos A. Mitrophanous, Pippa A Radcliffe, Helen Sang

المصدر: McGrew, M, Sherman, A, Lillico, S, Ellard, F M, Radcliffe, P A, Gilhooley, H, Mitrophanous, K A, Cambray, N, Wilson, V & Sang, H 2008, ' Localised axial progenitor cell populations in the avian tail bud are not committed to a posterior Hox identity ', Development, vol. 135, no. 13, pp. 2289-2299 . https://doi.org/10.1242/dev.022020

مصطلحات موضوعية: Tail, animal structures, Cellular differentiation, Population, Cell Count, Chick Embryo, Biology, Animals, Genetically Modified, Hox genes, Mice, Notochord, Paraxial mesoderm, medicine, Animals, Progenitor cell, education, Molecular Biology, Homeodomain Proteins, Neurons, education.field_of_study, Chordoneural hinge, Stem Cells, Gene Expression Regulation, Developmental, Cell Differentiation, Anatomy, Cell biology, Gastrulation, Transplantation, Transgenic chicken, medicine.anatomical_structure, Tail bud, embryonic structures, Stem cell, Developmental Biology, Stem Cell Transplantation

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41cafdae4271c5d93018d0c32ae3deb5
https://pubmed.ncbi.nlm.nih.gov/18508860

المؤلفون: K A Mitrophanous, Pippa A Radcliffe, E J Custard, G L Beard, Fraser J. Wilkes, Susan M. Kingsman, C J M Sion

المصدر: Gene therapy. 15(4)

مصطلحات موضوعية: animal diseases, Genetic enhancement, Genetic Vectors, Hemophilia A, Polymerase Chain Reaction, Virus, Viral vector, Cell Line, hemic and lymphatic diseases, Genetics, Humans, Codon, Promoter Regions, Genetic, Molecular Biology, Gene, Reporter gene, Factor VIII, biology, Genetic Therapy, biology.organism_classification, Virology, Vesicular stomatitis virus, Lentivirus, Pseudotyping, Molecular Medicine, Infectious Anemia Virus, Equine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ea4b1ceaae5dafa7d58601c49305673
https://pubmed.ncbi.nlm.nih.gov/18046428

المؤلفون: Anastasios Georgiadis, Faisal A. Al-Allaf, Brian W. Bigger, K. Mosley, Kyriacos A. Mitrophanous, A Mistry, Geoffrey Kemball-Cook, Suzanne M. K. Buckley, M Nivsarkar, Charles Coutelle, Simon N. Waddington, Lisa G. Gregory, H. Terence Cook, Edward G. D. Tuddenham, Adrian J. Thrasher, Mairi Brittan, Robin R. Ali, Michael Themis, Maxine V. Holder, Pippa A Radcliffe

المصدر: Blood. 104(9)

مصطلحات موضوعية: Male, Cellular immunity, Immunology, Genetic Vectors, Mice, Inbred Strains, Biochemistry, Hemophilia B, Factor IX, Mice, Pregnancy, Coagulopathy, Immune Tolerance, Medicine, Animals, Humans, Placental Circulation, Blood Coagulation, Clotting factor, Fetal Therapies, biology, business.industry, Genetic transfer, Lentivirus, Cell Biology, Hematology, Genetic Therapy, Coagulation Factor IX, medicine.disease, Phenotype, Coagulation, biology.protein, Female, Antibody, business, Immunocompetence, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8358bd2a4bd3e94020beea01688fb175
https://pubmed.ncbi.nlm.nih.gov/15231566

المؤلفون: W. A. Ritchie, Kyriacos A. Mitrophanous, Romi N. Pena, C. Bruce A. Whitelaw, A. John Clark, Pippa A Radcliffe, Jo M. Rowe, Ailsa J Carlisle, Tim King, F M Ellard

المصدر: Whitelaw, C B A, Radcliffe, P A, Ritchie, W A, Carlisle, A, Ellard, F M, Pena, R N, Rowe, J, Clark, A J, King, T J & Mitrophanous, K A 2004, ' Efficient generation of transgenic pigs using equine infectious anaemia virus (EIAV) derived vector ', FEBS Letters, vol. 571, no. 1-3, pp. 233-6 . https://doi.org/10.1016/j.febslet.2004.06.076

مصطلحات موضوعية: Livestock, Swine, Zygote, Transgene, Genetic Vectors, Green Fluorescent Proteins, Biophysics, Biochemistry, Transgenic, Green fluorescent protein, Animals, Genetically Modified, Structural Biology, Genes, Reporter, Genetics, Animals, Vector (molecular biology), Molecular Biology, Microinjection, Gene, Equine infectious anaemia virus, Pig, biology, Lentivirus, Gene Transfer Techniques, Cell Biology, biology.organism_classification, Embryo Transfer, Virology, Genetically modified organism, Blot, Blotting, Southern, Luminescent Proteins, Female, Biotechnology, Infectious Anemia Virus, Equine

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2642144e6ef33834660de3b2047dca0b
https://pubmed.ncbi.nlm.nih.gov/15280048

المؤلفون: Jonathan B, Rohll, Kyriacos A, Mitrophanous, Enca, Martin-Rendon, Fiona M, Ellard, Pippa A, Radcliffe, Nicholas D, Mazarakis, Susan M, Kingsman

المصدر: Methods in enzymology. 346

مصطلحات موضوعية: Viral Proteins, Evaluation Studies as Topic, Genetic Vectors, Humans, RNA-Directed DNA Polymerase, Genome, Viral, Virus Replication, Sensitivity and Specificity, Cell Line, Infectious Anemia Virus, Equine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::74761bef666d2fa867b7c2d0493dfcd2
https://pubmed.ncbi.nlm.nih.gov/11883086

المؤلفون: Fiona Margaret Ellard, Enca Martin-Rendon, Pippa A Radcliffe, Kyriacos A. Mitrophanous, Nicholas D. Mazarakis, Susan M. Kingsman, Jonathan Rohll

مصطلحات موضوعية: Text mining, Viral replication, business.industry, MEDLINE, Production (economics), Computational biology, Biology, business, Genome

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::4e1dc90e9cd2afbbaa7255d54518487c
https://doi.org/10.1016/s0076-6879(02)46072-7

المؤلفون: Leah A. Vardy, Takashi Toda, Pippa A. Radcliffe

المصدر: FEBS letters. 468(1)

مصطلحات موضوعية: Protein Folding, Saccharomyces cerevisiae Proteins, G protein, Molecular Sequence Data, Biophysics, Microtubule, GTP-binding protein, Saccharomyces cerevisiae, Biology, Biochemistry, Microtubules, Cofactor, Fungal Proteins, Structural Biology, GTP-Binding Proteins, Cell polarity, Schizosaccharomyces, Genetics, Homologous chromosome, Humans, ARF-like protein, Cloning, Molecular, Molecular Biology, Conserved Sequence, Phylogeny, Polarity (international relations), Sequence Homology, Amino Acid, Cell Biology, Fission yeast, Yeast, Cell biology, biology.protein, Schizosaccharomyces pombe Proteins, Microtubule-Associated Proteins, Sequence Alignment, Biogenesis, Cell Division, Gene Deletion

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38ccddeb7ed61ea1ae3797005527598a
https://pubmed.ncbi.nlm.nih.gov/10683446

المؤلفون: Susan M. Kingsman, Emily J. Custard, Kyriacos A. Mitrophanous, Pippa A Radcliffe, Fraser J. Wilkes

المصدر: Molecular Therapy. 11:S231-S232

مصطلحات موضوعية: Pharmacology, biology, animal diseases, viruses, Genetic enhancement, Haemophilia A, biology.organism_classification, medicine.disease, Virology, Immune system, Drug Discovery, Lentivirus, Immunology, Genetics, medicine, Molecular Medicine, Vector system, Equine infectious anaemia virus, Molecular Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::2d5d11f678d5fe74c6afe28f8b37df1d
https://doi.org/10.1016/j.ymthe.2005.07.139

المؤلفون: Susan M. Kingsman, Janine M. Carthy, Gareth S. Ralph, Pippa A Radcliffe, Kyriacos A. Mitrophanous, Nicholas D. Mazarakis, Denise M. Day, Mimoun Azzouz

المصدر: Molecular Therapy. 11:S23

مصطلحات موضوعية: Pharmacology, Genetically modified mouse, Genetic enhancement, Mutant, Biology, medicine.disease, Molecular biology, Viral vector, Cell biology, RNA interference, Drug Discovery, Genetics, medicine, Molecular Medicine, Gene silencing, Amyotrophic lateral sclerosis, Molecular Biology, Gene

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::9145c272c7fce8a30bf806e2106aae94
https://doi.org/10.1016/j.ymthe.2005.06.083

المؤلفون: Caroline V. Hacker, James Miskin, Daniel Chipchase, Susan M. Kingsman, Pippa A Radcliffe, Kyriacos A. Mitrophanous, Nicholas D. Mazarakis

المصدر: Molecular Therapy. 11:S153

مصطلحات موضوعية: Pharmacology, Genetics, biology, Genetic enhancement, Transgene, Woodchuck hepatitis virus, Spinal muscular atrophy, Gene delivery, biology.organism_classification, medicine.disease, Virology, Insertional mutagenesis, Transduction (genetics), Open reading frame, Drug Discovery, medicine, Molecular Medicine, Molecular Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::1e285111fa6df44c432d76e4a3285e28
https://doi.org/10.1016/j.ymthe.2005.06.398

المؤلفون: K A Mitrophanous, Pippa A Radcliffe, Colin P. J. Glover, Alison Bienemann, James B. Uney, Nicholas D. Mazarakis

المصدر: Molecular Therapy. 9:S241

مصطلحات موضوعية: Pharmacology, medicine.medical_specialty, Pituitary gland, Vasopressin, Kidney, Reabsorption, Biology, medicine.disease, biology.organism_classification, Brattleboro rat, Endocrinology, medicine.anatomical_structure, Hypothalamus, Internal medicine, Drug Discovery, Diabetes insipidus, Genetics, medicine, Molecular Medicine, Magnocellular cell, Molecular Biology, hormones, hormone substitutes, and hormone antagonists

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::f79c199f70366f06b884ef72677dcb70
https://doi.org/10.1016/j.ymthe.2004.06.571

المؤلفون: Suzanne M. K. Buckley, Charles Coutelle, Pippa A Radcliffe, Terrence Cook, L Lawrence, Michael Themis, Kyriacos A. Mitrophanous, Nick Mazarakis, Faisal A. Allaf, Lisa G. Gregory, Brian W. Bigger, Susan M. Kingsman, Fiona E. Ellard, Mimoun Azzouz, Simon N. Waddington, Maxine V. Holder, Lucy E. Walmsley

المصدر: Molecular Therapy. 9:S91

مصطلحات موضوعية: Pharmacology, Transgene, Genetic enhancement, Duchenne muscular dystrophy, Gene targeting, Gene delivery, Biology, Bioinformatics, medicine.disease, Molecular biology, Drug Discovery, Gene expression, Genetics, medicine, Molecular Medicine, Myocyte, ITGA7, Molecular Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::5f89556863558f552625dbcadb5159c0
https://doi.org/10.1016/j.ymthe.2004.06.164

المؤلفون: Terence Cook, Michael Themis, T Georgiadis, Simon N. Waddington, Maxine V. Holder, Edward G. D. Tuddenham, Kyriacos A. Mitrophanous, Pippa A Radcliffe, K. Mosley, Geoffrey Kemball-Cook, Faisal A. Al-Allaf, Lisa G. Gregory, M Nivsarkar, Brian W. Bigger, Adrian J. Thrasher, Suzanne M. K. Buckley, Charles Coutelle, Robin R. Ali, A Mistry, Mairi Brittan

المصدر: Molecular Therapy. 9:S15

مصطلحات موضوعية: Pharmacology, Cellular immunity, Genetic enhancement, Biology, medicine.disease, Virology, Viral vector, Drug Discovery, Immunology, Genetics, medicine, biology.protein, Molecular Medicine, Immunohistochemistry, Haemophilia B, Vector (molecular biology), Antibody, Molecular Biology, Factor IX, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::99ef8962e98e55f5c3c7c7e645bff829
https://doi.org/10.1016/j.ymthe.2004.05.059

المؤلفون: Georgina L. Beard, Pippa A Radcliffe, Kyriacos A. Mitrophanous, Susan M. Kingsman, Fraser J. Wilkes

المصدر: Molecular Therapy. 9:S64

مصطلحات موضوعية: Pharmacology, biology, Genetic enhancement, Haemophilia A, biology.organism_classification, medicine.disease, Haemophilia, Virology, Viral vector, Immune system, hemic and lymphatic diseases, Drug Discovery, Lentivirus, Genetics, medicine, Molecular Medicine, Equine infectious anaemia virus, Vector (molecular biology), Molecular Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::debd088dfddb17f352d8d9f2c8ac82af
https://doi.org/10.1016/j.ymthe.2004.06.128