المؤلفون: Selvapriya Kumaran, Chandrasekar sanyasi, Suresh Kumar Muthuvel

المصدر: Discover Applied Sciences, Vol 6, Iss 11, Pp 1-18 (2024)

مصطلحات موضوعية: Protein disulfide isomerase, Molecular docking, Molecular dynamics simulation, Peptide interaction, Secondary structure transition, Domain motion, Science (General), Q1-390

وصف الملف: electronic resource

Relation: https://doaj.org/toc/3004-9261

URL الوصول: https://doaj.org/article/5ab69c0010204846bbe8fa7bcf4f7406

المؤلفون: Courela, João Pedro Maneta

مصطلحات موضوعية: VIH, SIDA, Péptidos inibidores de fusão, Membranas biológicas, Dinâmica molecular, Interações lípido-péptido, Simulação de biomembranas, HIV, AIDS, Fusion inhibitor peptides, Biological membranes, Molecular dynamics, Lipid-peptide interaction, Biomembrane simulations

Relation: Departamento de Químca; l42951@alunos.uevora.pt; 303

الاتاحة: http://hdl.handle.net/10174/37193

المؤلفون: Ko, Myung Soo, Cohen, Samantha N, Polley, Smarajit, Mahata, Sushil K, Biswas, Tapan, Huxford, Tom, Ghosh, Gourisankar

المصدر: Journal of Biological Chemistry. 298(5)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Cancer, Humans, I-kappa B Kinase, NF-kappa B, Polyubiquitin, Protein Binding, NF-κB, enzyme inactivation, peptide interaction, polyubiquitin chain, protein kinase, Chemical Sciences, Medical and Health Sciences, Biochemistry & Molecular Biology, Biological sciences, Biomedical and clinical sciences, Chemical sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/2332x3x5
https://escholarship.org/content/qt2332x3x5/qt2332x3x5.pdf

المؤلفون: Gielnik, Maciej, Zhukova, Lilia, Zhukov, Igor, Gräslund, Astrid, Kozak, Maciej, Wärmländer, Sebastian K. T. S.

المصدر: Acta Biochimica Polonica. 69(1):257-261

مصطلحات موضوعية: Creutzfeldt-Jakob disease, AFM imaging, amyloid, drug design, drug transport, protein-peptide interaction

وصف الملف: print

URL الوصول: https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-202601
https://doi.org/10.18388/abp.2020_5679

المؤلفون: Gu, S, Bradley-Clarke, J, Rose, R-S, Warren, MJ, Pickersgill, RW

مصطلحات موضوعية: bacterial metabolism, cell compartmentalization, enzyme catalysis, peptide interaction, protein self‐assembly

وصف الملف: 107357 - ?

Relation: J Biol Chem; Shuang Gu, Jack Bradley-Clarke, Ruth-Sarah Rose, Martin J. Warren, Richard W. Pickersgill, Enzyme-cargo encapsulation peptides bind between tessellating tiles of the bacterial microcompartment shell, Journal of Biological Chemistry, 2024, 107357, ISSN 0021-9258, https://doi.org/10.1016/j.jbc.2024.107357. (https://www.sciencedirect.com/science/article/pii/S0021925824018581) Abstract: Bacterial microcompartments are prokaryotic organelles comprising encapsulated enzymes within a thin protein shell. They facilitate metabolic processing including propanediol, choline, glycerol, and ethanolamine utilization, and they accelerate carbon fixation in cyanobacteria. Enzymes targeted to the inside of the microcompartment frequently possess a cargo-encapsulation peptide, but the site to which the peptide binds is unclear. We provide evidence that the encapsulation peptides bind to the hydrophobic groove formed between tessellating subunits of the shell proteins. In silico docking studies provide a compelling model of peptide binding to this prominent hydrophobic groove. This result is consistent with the now widely accepted view that the convex side of the shell oligomers faces the lumen of the microcompartment. Binding of the encapsulation peptide to the groove between tessellating shell protein tiles explains why it has been difficult to define the peptide binding site using other methods, provides a mechanism by which encapsulation-peptide bearing enzymes can promote shell assembly, and explains how the presence of cargo affects the size and shape of the bacterial microcompartment. This knowledge may be exploited in engineering microcompartments or in disease prevention by hampering cargo-encapsulation. Keywords: bacterial metabolism; cell compartmentalization; enzyme catalysis; peptide interaction; protein self‐assembly; https://qmro.qmul.ac.uk/xmlui/handle/123456789/96962

الاتاحة: https://qmro.qmul.ac.uk/xmlui/handle/123456789/96962
https://doi.org/10.1016/j.jbc.2024.107357

المؤلفون: Larisa I. Fedoreyeva, Tatiana A. Dilovarova, Boris F. Vanyushin, Inna A. Chaban, Neonila V. Kononenko

المصدر: AIMS Biophysics, Vol 9, Iss 2, Pp 113-129 (2022)

مصطلحات موضوعية: peptide mkasaa, dna methylation, rddm, rna-peptide interaction, Biology (General), QH301-705.5, Biotechnology, TP248.13-248.65

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2377-9098

URL الوصول: https://doaj.org/article/5461a2b6f62648b39e51fe9302c439f5

المؤلفون: Thakkar, Ravindra, Comer, Jeffrey

مصطلحات موضوعية: peptide design, molecular dynamics simulation, COVID-19 therapy, Spike protein inhibitor, NAMD, Free energy calculation, Biolayer interferometry, protein-peptide interaction

Relation: https://zenodo.org/communities/integrativemodeling; https://zenodo.org/communities/md-simulation-protein; https://zenodo.org/communities/charmm36; https://doi.org/10.5281/zenodo.7844170; https://doi.org/10.5281/zenodo.7844171; oai:zenodo.org:7844171

الاتاحة: https://doi.org/10.5281/zenodo.7844171

المؤلفون: Kelly Bugatti, Andrea Sartori, Lucia Battistini, Crescenzo Coppa, Emiel Vanhulle, Sam Noppen, Becky Provinciael, Lieve Naesens, Annelies Stevaert, Alessandro Contini, Kurt Vermeire, Franca Zanardi

المساهمون: Bugatti, Kelly, Sartori, Andrea, Battistini, Lucia, Coppa, Crescenzo, Vanhulle, Emiel, Noppen, Sam, Provinciael, Becky, Naesens, Lieve, Stevaert, Annelie, Contini, Alessandro, Vermeire, Kurt, Zanardi, Franca

مصطلحات موضوعية: cyclic peptide, protein–peptide interaction, antiviral agent, drug design, receptor-binding domain (RBD), solid-phase peptide synthesi, polymyxin-like peptidomimetics

Relation: info:eu-repo/semantics/altIdentifier/wos/WOS:001195817200001; volume:24; issue:10; firstpage:8765; numberofpages:21; journal:INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES; https://hdl.handle.net/11381/2945311

الاتاحة: https://hdl.handle.net/11381/2945311
https://doi.org/10.3390/ijms24108765
https://www.mdpi.com/1422-0067/24/10/8765

المؤلفون: Sven Wijngaarden, Chunsong Yang, Carlos Vela-Rodríguez, Lari Lehtiö, Herman S. Overkleeft, Bryce M. Paschal, Dmitri V. Filippov

مصطلحات موضوعية: Biophysics, Biochemistry, Pharmacology, Biotechnology, Infectious Diseases, Astronomical and Space Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, significantly higher affinity, ribofuranosylcysteine building block, use synthetic peptides, synthetic dual cysteine, ribosylated cysteine peptides, ribosyl binding macrodomains, peptide interaction since, adp ribosylated peptides, parp9 complex recognizes, dual adp, substrate modification, single adp, reader contribute, prepared using, parp9 complex, parp9 assembly, novel solid, multivalent interactions, multiple cysteines, k <, deletion mutant, androgen receptor, >< sub

Relation: https://figshare.com/articles/journal_contribution/Synthetic_Dual_Cysteine-ADP_Ribosylated_Peptides_from_the_Androgen_Receptor_are_Recognized_by_the_DTX3L_PARP9_Complex/24530764

الاتاحة: https://doi.org/10.1021/acschembio.3c00305.s001
https://figshare.com/articles/journal_contribution/Synthetic_Dual_Cysteine-ADP_Ribosylated_Peptides_from_the_Androgen_Receptor_are_Recognized_by_the_DTX3L_PARP9_Complex/24530764

المؤلفون: Jee Eun Kang, Ji Hae Jun, Jung Hyun Kwon, Ju-Hyun Lee, Kidong Hwang, Sungjong Kim, Namhee Jeong

المصدر: Genes; Volume 14; Issue 7; Pages: 1476

مصطلحات موضوعية: liquid–liquid phase separation, protein oligomerization, GO, domain–domain interaction, domain linker, intrinsically disordered regions, domain–peptide interaction, beta sheet, transmembrane helices, post-translational modification

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Bioinformatics; https://dx.doi.org/10.3390/genes14071476

الاتاحة: https://doi.org/10.3390/genes14071476

المؤلفون: Ayse Ön, Djenana Vejzovic, James Jennings, Lena Parigger, Robert A. Cordfunke, Jan Wouter Drijfhout, Karl Lohner, Nermina Malanovic

المصدر: Antibiotics; Volume 12; Issue 7; Pages: 1163

مصطلحات موضوعية: LPS, lipid–peptide interaction, membrane permeabilization

وصف الملف: application/pdf

Relation: Antimicrobial Peptides; https://dx.doi.org/10.3390/antibiotics12071163

الاتاحة: https://doi.org/10.3390/antibiotics12071163

المؤلفون: Nathalia Calderón-Rivera, Jessica Múnera-Jaramillo, Sara Jaramillo-Berrio, Elizabeth Suesca, Marcela Manrique-Moreno, Chad Leidy

المصدر: Membranes; Volume 13; Issue 3; Pages: 304

مصطلحات موضوعية: Staphylococcus aureus, antimicrobial peptides, lipid-peptide interaction, membrane active peptides, fluorescence spectroscopy, infrared spectroscopy

وصف الملف: application/pdf

Relation: Biological Membrane Composition and Structures; https://dx.doi.org/10.3390/membranes13030304

الاتاحة: https://doi.org/10.3390/membranes13030304

المؤلفون: Madsen, Jesper J., Petersen, Jacob E., Christensen, Dan P., Hansen, Jakob B., Schwartz, Thue W., Frimurer, Thomas M., Olsen, Ole H.

المصدر: Madsen , J J , Petersen , J E , Christensen , D P , Hansen , J B , Schwartz , T W , Frimurer , T M & Olsen , O H 2023 , ' Deciphering specificity and cross-reactivity in tachykinin NK1 and NK2 receptors ' , Journal of Biological Chemistry , vol. 299 , no. 12 , 105438 . https://doi.org/10.1016/j.jbc.2023.105438

مصطلحات موضوعية: cross-reactivity, G protein-coupled receptor (GPCR), molecular dynamics, molecular modeling, mutagenesis, peptide interaction

وصف الملف: application/pdf

الاتاحة: https://researchprofiles.ku.dk/da/publications/deciphering-specificity-and-crossreactivity-in-tachykinin-nk1-and-nk2-receptors(9f80a3ac-f566-4e0b-870d-422a5dd00f89).html
https://doi.org/10.1016/j.jbc.2023.105438
https://curis.ku.dk/ws/files/378806223/PIIS0021925823024663.pdf

المؤلفون: Krotee, Pascal, Griner, Sarah L, Sawaya, Michael R, Cascio, Duilio, Rodriguez, Jose A, Shi, Dan, Philipp, Stephan, Murray, Kevin, Saelices, Lorena, Lee, Ji, Seidler, Paul, Glabe, Charles G, Jiang, Lin, Gonen, Tamir, Eisenberg, David S

المصدر: Journal of Biological Chemistry. 293(8)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Dementia, Neurosciences, Acquired Cognitive Impairment, Brain Disorders, Aging, Alzheimer's Disease, Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD), Neurodegenerative, 2.1 Biological and endogenous factors, Neurological, Metabolic and endocrine, Amino Acid Substitution, Amyloid beta-Peptides, Animals, Cell Line, Tumor, Computational Biology, Crystallography, X-Ray, Drug Design, HEK293 Cells, Humans, Hypoglycemic Agents, Insulin-Secreting Cells, Islet Amyloid Polypeptide, Mice, Microscopy, Electron, Transmission, Models, Molecular, Mutation, Neurofibrillary Tangles, Neurons, Nootropic Agents, Peptide Fragments, Protein Aggregation, Pathological, Rats, Recombinant Proteins, amyloid, amyloid-β, crystal structure, electron diffraction, human islet amyloid polypeptide, inhibitor, peptide interaction, Chemical Sciences, Medical and Health Sciences, Biochemistry & Molecular Biology, Biological sciences, Biomedical and clinical sciences, Chemical sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/6368r0x1
https://escholarship.org/content/qt6368r0x1/qt6368r0x1.pdf

المساهمون: Min, Jinrong [Univ. of Toronto, ON (Canada)]

المصدر: Journal of Biological Chemistry; 292; 14

وصف الملف: Medium: ED; Size: p. 5655-5664

URL الوصول: http://www.osti.gov/scitech/servlets/purl/1368285

المؤلفون: Hesham ElAbd, Yana Bromberg, Adrienne Hoarfrost, Tobias Lenz, Andre Franke, Mareike Wendorff

المصدر: BMC Bioinformatics, Vol 21, Iss 1, Pp 1-14 (2020)

مصطلحات موضوعية: Deep-learning, Amino acid encoding, Amino acids embedding, Protein-protein interaction (PPI), HLA-II peptide interaction, Convoluted-neural network (CNN), Computer applications to medicine. Medical informatics, R858-859.7, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://link.springer.com/article/10.1186/s12859-020-03546-x; https://doaj.org/toc/1471-2105

URL الوصول: https://doaj.org/article/41b767d5be2544e29330358d3a231817

المؤلفون: Qian Liu, Jing Lin, Li Wen, Shaozhou Wang, Peng Zhou, Li Mei, Shuyong Shang

المصدر: Frontiers in Genetics, Vol 12 (2022)

مصطلحات موضوعية: computational peptidology, peptide quantitative structure-activity relationship, domain-peptide interaction, amino acid descriptor, statistical modeling, machine learning, Genetics, QH426-470

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fgene.2021.800857/full; https://doaj.org/toc/1664-8021

URL الوصول: https://doaj.org/article/8f69f325eac0460b9b40f18acba29943

المؤلفون: Gasbarri C., Rosignoli S., Janson G., Boi D., Paiardini A.

المساهمون: Gasbarri, C., Rosignoli, S., Janson, G., Boi, D., Paiardini, A.

مصطلحات موضوعية: PepThreader, protein–peptide interaction, protein–protein interaction, template-based modeling

Relation: info:eu-repo/semantics/altIdentifier/pmid/35204702; info:eu-repo/semantics/altIdentifier/wos/WOS:000763712100001; volume:12; issue:2; firstpage:201; journal:BIOMOLECULES; http://hdl.handle.net/11573/1625113; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85123311952

الاتاحة: http://hdl.handle.net/11573/1625113
https://doi.org/10.3390/biom12020201

المؤلفون: Rivera-Sanchez, Sandra Patricia, Ocampo-Ibáñez, Iván Darío, Liscano, Yamil, Martínez, Natalia, Muñoz, Isamar, Manrique-Moreno, Marcela, Martinez-Martinez, Luis, Oñate-Garzon, José

مصطلحات موضوعية: cationic antimicrobial peptides, colistin-resistant Pseudomonas aeruginosa, membrane–peptide interaction, model membranes

وصف الملف: application/pdf

Relation: http://hdl.handle.net/10668/21553; PMC9230736; https://www.mdpi.com/1999-4923/14/6/1248/pdf?version=1655110798; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9230736/pdf

الاتاحة: http://hdl.handle.net/10668/21553
https://doi.org/10.3390/pharmaceutics14061248
https://www.mdpi.com/1999-4923/14/6/1248/pdf?version=1655110798
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9230736/pdf

المؤلفون: Matko Maleš, Larisa Zoranić

المصدر: Membranes; Volume 12; Issue 9; Pages: 891

مصطلحات موضوعية: α-helical peptides, antimicrobial peptides, mode of action, molecular dynamic simulations, membrane-peptide interaction, aggregation

وصف الملف: application/pdf

Relation: Biological Membrane Dynamics and Computation; https://dx.doi.org/10.3390/membranes12090891

الاتاحة: https://doi.org/10.3390/membranes12090891