المؤلفون: Amrita V Kamath, Simon P Williams, Sherry Bullens, Kyra J Cowan, Yvonne Stenberg, Simon R Cherry, Stephen Rendig, David L Kukis, Chris Griesemer, Lisa A Damico-Beyer, Stuart Bunting

المصدر: PLoS ONE, Vol 7, Iss 9, p e45116 (2012)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC3444451?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/4f40473cc18b497c9d4f82c1f6d4ffc1

المؤلفون: Priti S. Hegde, Mark R. Lackner, Garret M. Hampton, Amy Peterson, Premal Patel, Robert L. Yauch, Mark Merchant, Kyra J. Cowan, Luciana Burton, Vaishali Parab, Congfen Li, Elicia Penuel

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::445d4f7af40273c1e9422fbfa7d4016e
https://doi.org/10.1158/1535-7163.22499679

المؤلفون: Priti S. Hegde, Mark R. Lackner, Garret M. Hampton, Amy Peterson, Premal Patel, Robert L. Yauch, Mark Merchant, Kyra J. Cowan, Luciana Burton, Vaishali Parab, Congfen Li, Elicia Penuel

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::754e28d16bdf0548b4252eaebc7b8e2b
https://doi.org/10.1158/1535-7163.22499676

المؤلفون: Priti S. Hegde, Mark R. Lackner, Garret M. Hampton, Amy Peterson, Premal Patel, Robert L. Yauch, Mark Merchant, Kyra J. Cowan, Luciana Burton, Vaishali Parab, Congfen Li, Elicia Penuel

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::0d781b118706dbc3f4a33a170feef898
https://doi.org/10.1158/1535-7163.c.6536214

المؤلفون: Julie DeMartino, Jeff Kraines, Hugues Dolgos, Kerstin Kleinschmidt-Dörr, Robert Townsend, Anne Gigout, Flavie Moreau, Kyra J. Cowan

مصطلحات موضوعية: Drug Discovery, Pharmacology

Relation: url:https://www.openaccessrepository.it/communities/itmirror; https://www.openaccessrepository.it/record/83893

الاتاحة: https://www.openaccessrepository.it/record/83893
https://doi.org/10.1016/j.drudis.2020.03.015

المؤلفون: Darshana Jani, Robin Marsden, Michele Gunsior, Laura Schild Hay, Bethany Ward, Kyra J. Cowan, Mitra Azadeh, Breann Barker, Liching Cao, Kristin R. Closson, Kelly Coble, Sanjay L. Dholakiya, Julie Dusseault, Amanda Hays, Carina Herl, Michael E. Hodsdon, Susan C. Irvin, Susan Kirshner, Gerry Kolaitis, Nadia Kulagina, Seema Kumar, Ching Ha Lai, Francesco Lipari, Susana Liu, Keith D. Merdek, Ioana R. Moldovan, Reza Mozaffari, Luying Pan, Corina Place, Veerle Snoeck, Marta Starcevic Manning, Dennis Stocker, Magdalena Tary-Lehmann, Amy Turner, Inna Vainshtein, Daniela Verthelyi, William T. Williams, Haoheng Yan, Weili Yan, Lili Yang, Lin Yang, Jennifer Zemo, Zhandong Don Zhong

المصدر: The AAPS journalReferences. 24(6)

مصطلحات موضوعية: Pharmaceutical Science, Antibodies, Neutralizing, Antibodies

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6785f559d1c0afdbcb7a3a0839baf45
https://pubmed.ncbi.nlm.nih.gov/36307592

المؤلفون: Anne Gigout, Daniela Werkmann, Stephanie Menges, Christian Brenneis, Frances Henson, Kyra J. Cowan, Djordje Musil, Christian S. Thudium, Hans Gühring, Martin Michaelis, Kerstin Kleinschmidt‐Doerr

المصدر: Arthritisrheumatology (Hoboken, N.J.)REFERENCES.

مصطلحات موضوعية: Rheumatology, Immunology, Immunology and Allergy

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afd67f19e8ce2e025bc961c0a7fd27ee
https://pubmed.ncbi.nlm.nih.gov/36054172

المؤلفون: Kyra J. Cowan, Lars Karlsson, Joanne Goodman, Linda Terry, Hans Ulrichts, Ulrich Kunz, Michaela Golob, Lauren Stevenson, Philip Timmerman, Robert Nelson

المصدر: Bioanalysis. 12:1427-1437

مصطلحات موضوعية: Bioanalysis, business.industry, 010401 analytical chemistry, Clinical Biochemistry, Context (language use), General Medicine, Computational biology, 030226 pharmacology & pharmacy, 01 natural sciences, Method development, 0104 chemical sciences, Analytical Chemistry, Europe, 03 medical and health sciences, Medical Laboratory Technology, 0302 clinical medicine, Drug development, Humans, Medicine, Biomarker (medicine), Biological Assay, General Pharmacology, Toxicology and Pharmaceutics, business, Biomarkers

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e167908fbf2f113ada5641a874322e97
https://doi.org/10.4155/bio-2020-0243

المؤلفون: Joanne Goodman, Jonas Blaes, John Cook, Kyra J. Cowan, Philip Timmerman, Joanna Grudzinska-Goebel, Madeleine Dahlbäck, Robert Nelson, Anna Laurén, Deborah McManus, Susanne Pihl

المصدر: Bioanalysis. 13(7)

مصطلحات موضوعية: 0303 health sciences, Bioanalysis, Modalities, business.industry, Immunogenicity, 010401 analytical chemistry, Clinical Biochemistry, General Medicine, 01 natural sciences, Antibodies, 0104 chemical sciences, Analytical Chemistry, Europe, 03 medical and health sciences, Medical Laboratory Technology, Strategic approach, Antibody Formation, Medicine, Humans, Engineering ethics, Biological Assay, General Pharmacology, Toxicology and Pharmaceutics, business, 030304 developmental biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd995f3a60ee4e75636d3730008c4faa
https://pubmed.ncbi.nlm.nih.gov/33729007

المؤلفون: Medha Kamat, Damien Fink, Yuda Zhu, Yan G. Ni, Mark Cameron, Renee Riffon, Lakshmi Amaravadi, Kyra J. Cowan, Darshana Jani, Robert Neely, Lindsay King, Paul Rhyne

المصدر: The AAPS Journal. 19:1550-1563

مصطلحات موضوعية: Computer science, 010401 analytical chemistry, Pharmacology toxicology, Proteins, Pharmaceutical Science, Bioinformatics, 030226 pharmacology & pharmacy, 01 natural sciences, 0104 chemical sciences, 03 medical and health sciences, 0302 clinical medicine, Calibration, Biomarker (medicine), Biochemical engineering, Biomarkers, Selection (genetic algorithm)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7c8d89302e5554d6f843fa0e7bf540a
https://doi.org/10.1208/s12248-017-0146-9

المؤلفون: Sharmila Rajan, Thomas Gelzleichter, Amos Baruch, Junichiro Sonoda, C. Andrew Boswell, Dale Stevens, Eric Stefanich, Danielle Mandikian, Kyra J. Cowan

المصدر: mAbs. 9:1379-1388

مصطلحات موضوعية: Male, 0301 basic medicine, Receptor complex, FGF21, medicine.drug_class, Receptor expression, Immunology, Drug Evaluation, Preclinical, Adipose tissue, CHO Cells, Pharmacology, Biology, Diet, High-Fat, Monoclonal antibody, 03 medical and health sciences, Cricetulus, Report, Cricetinae, medicine, Animals, Immunology and Allergy, Tissue Distribution, Obesity, Receptor, Fibroblast Growth Factor, Type 1, Receptor, Adiponectin, Fibroblast growth factor receptor 1, Antibodies, Monoclonal, Fibroblast Growth Factors, Mice, Inbred C57BL, Macaca fascicularis, 030104 developmental biology, Adipose Tissue, Female

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfe09bafc48ef65e54437fd42a8236af
https://doi.org/10.1080/19420862.2017.1373923

المؤلفون: Amos Baruch, Robert Kahn, Andrew S. Peterson, Cecilia P.C. Chiu, Whittemore G. Tingley, Nageshwar Budha, Daniel Kirchhofer, Kyra J. Cowan, Yan Wu, Diana Luca, Maya Leabman, John C. Davis

المصدر: Clinical Cardiology. 40:503-511

مصطلحات موضوعية: 0301 basic medicine, business.industry, Cholesterol, PCSK9, Atorvastatin, General Medicine, 030204 cardiovascular system & hematology, Pharmacology, 03 medical and health sciences, Subcutaneous injection, chemistry.chemical_compound, 030104 developmental biology, 0302 clinical medicine, Pharmacokinetics, chemistry, LDL receptor, Medicine, Kexin, lipids (amino acids, peptides, and proteins), Cardiology and Cardiovascular Medicine, business, Lipoprotein, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::a11e78e3afbbef19b146c535ac36493d
https://doi.org/10.1002/clc.22687

المؤلفون: Akiko Ishii-Watabe, Albert Torri, Rong Zeng, Daniel Kramer, Steven P. Piccoli, David J. Uhlinger, Stephanie Fraser, Patricia Siguenza, Afshin Safavi, John Smeraglia, Apollon Papadimitriou, Yan G. Ni, Susan M. Richards, Kyra J. Cowan, Alessandra Vitaliti, Lakshmi Amaravadi, Boris Gorovits, Gustavo Mendes Lima Santos, John Kadavil, Sam Haidar, Jan Welink, Yongchang Qiu, João Pedras-Vasconcelos, Chan C. Whiting, Li Xue, Christina Satterwhite, John Kamerud, Swati Gupta, Natasha Savoie, Herbert Birnboeck, Yoshiro Saito, Paul Rhyne, Fabrizio Galliccia, Laurent Cocea, Stephanie Croft, Bonnie Wu, Theingi M. Thway, Virginia Litwin, Corinna Krinos-Fiorotti, Darshana Jani, Charles S Hottenstein, Vinita Gupta, Roland F Staack, Fabio Garofolo, Eginhard Schick, Kara Scheibner, Meena Subramanyam, John Allinson, Renuka Pillutla, Robert Nelson, Flora Berisha, Martin Ullmann, Giane Sumner

المصدر: Bioanalysis. 8:2475-2496

مصطلحات موضوعية: Bioanalysis, Macromolecular Substances, Consensus Development Conferences as Topic, Clinical Biochemistry, Validation Studies as Topic, Ligands, 030226 pharmacology & pharmacy, 01 natural sciences, Mass Spectrometry, Analytical Chemistry, 03 medical and health sciences, Government Agencies, 0302 clinical medicine, White paper, Humans, General Pharmacology, Toxicology and Pharmaceutics, Chromatography, High Pressure Liquid, business.industry, Immunogenicity, 010401 analytical chemistry, Scientific excellence, Antibodies, Monoclonal, General Medicine, Data science, 0104 chemical sciences, Biotechnology, Medical Laboratory Technology, Biopharmaceutical, Business, Biomarkers

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a67282718390ee4d7f9eb9599bdcf67
https://doi.org/10.4155/bio-2016-4989

المؤلفون: Jeffrey Wallin, Vaishali Parab, Lawren Wu, Trung Nguy, Eric Wakshull, Melissa Cheu, Michael J. Townsend, Alyssa Morimoto, Joseph R. Arron, Kyra J. Cowan, Xiaoying Gao

المصدر: Bioanalysis. 8:2329-2340

مصطلحات موضوعية: medicine.medical_specialty, medicine.diagnostic_test, Computer science, 010401 analytical chemistry, Clinical Biochemistry, General Medicine, 01 natural sciences, 0104 chemical sciences, Analytical Chemistry, 03 medical and health sciences, Medical Laboratory Technology, Patient safety, 0302 clinical medicine, Drug development, Acceptance testing, 030220 oncology & carcinogenesis, Immunoassay, medicine, Biomarker (medicine), Medical physics, General Pharmacology, Toxicology and Pharmaceutics

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39be10116d53fe0ecc8f2da1c3d4d961
https://doi.org/10.4155/bio-2016-0184

المؤلفون: Kyra J Cowan

المصدر: Current Issues in Ligand Binding Assay Bioanalysis. :34-46

مصطلحات موضوعية: Chromatography, Calibration curve, Chemistry, Ligand binding assay

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::230ba9ecf4e2d76bd6819e9e1423c637
https://doi.org/10.4155/fseb2013.14.337

المؤلفون: Kyra J. Cowan, Feng Yang, Mark Z. Chen, Ambrose Williams, Terry Hudson, Shannon Liu, Nicole Valle, Timothy Tully, Junichiro Sonoda, Thomas Gelzleichter, Sharmila Rajan, Frank Macchi

المصدر: Journal of pharmacological and toxicological methods. 94(Pt 1)

مصطلحات موضوعية: 0301 basic medicine, Male, Bispecific antibody, Receptor complex, Mice, Obese, CHO Cells, Toxicology, Antibodies, Cell Line, 03 medical and health sciences, Mice, Cricetulus, Animals, Humans, Obesity, Receptor, Fibroblast Growth Factor, Type 1, Related impurities, Obese Mice, Pharmacology, Manufacturing process, Chemistry, Membrane Proteins, Highly selective, Combinatorial chemistry, Mice, Inbred C57BL, Molecular Weight, stomatognathic diseases, Disease Models, Animal, Drug Combinations, 030104 developmental biology, HEK293 Cells, Product (mathematics), Immunoglobulin G, Drug product, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7b66987db00744fc1e7acdc79bb85f9
https://pubmed.ncbi.nlm.nih.gov/29660397

المؤلفون: Kyra J. Cowan, Hans Hornauer, Robyn Rourick, Patricia Siguenza, Albert Geiger

المصدر: Bioanalysis. 9(12)

مصطلحات موضوعية: Immunoassay, Analyte, Chromatography, medicine.diagnostic_test, Computer science, Ligand binding assay, 010401 analytical chemistry, Clinical Biochemistry, Nanotechnology, General Medicine, Ligands, 01 natural sciences, 0104 chemical sciences, Analytical Chemistry, 03 medical and health sciences, Medical Laboratory Technology, 0302 clinical medicine, 030220 oncology & carcinogenesis, medicine, Cytokines, Humans, General Pharmacology, Toxicology and Pharmaceutics

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb9fcd4efb43e5f1aad0b4b89ae65425
https://pubmed.ncbi.nlm.nih.gov/28627218

المؤلفون: Robert F. Kelley, Laura DeForge, Kyra J. Cowan, Maya Leabman, Y. Gloria Meng, Suhasini Iyer

المصدر: mAbs. 5:896-903

مصطلحات موضوعية: Glycosylation, Immunology, Enzyme-Linked Immunosorbent Assay, Receptors, Fc, Plasma protein binding, Pharmacology, chemistry.chemical_compound, Cricetinae, Report, Animals, Immunology and Allergy, Receptor, chemistry.chemical_classification, Dose-Response Relationship, Drug, biology, Chinese hamster ovary cell, Wild type, Antibodies, Monoclonal, Genetic Variation, Molecular biology, Fragment crystallizable region, Amino acid, Macaca fascicularis, chemistry, biology.protein, Antibody, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdd72f541ae11adc6505fe61a2bd0922
https://doi.org/10.4161/mabs.26436

المؤلفون: Shijie Li, Kevin L. Grove, Sherry Bullens, Ganesh Kolumam, Paul Kievit, Nicholas van Bruggen, Lindsay Bader, Anna-Karin L. Robertson, Xiumin Li, Stuart Bunting, Björn Frendéus, Karin von Wachenfeldt, Amrita V. Kamath, Ilhem Messaoudi, Christine Valfridsson, Kyra J. Cowan

المصدر: Molecular Metabolism. 2(3):256-269

مصطلحات موضوعية: media_common.quotation_subject, Syk, Inflammation, 030204 cardiovascular system & hematology, Immune complex formation, 03 medical and health sciences, 0302 clinical medicine, Immune system, medicine, Internalization, Receptor, Molecular Biology, 030304 developmental biology, media_common, 0303 health sciences, Innate immune system, biology, business.industry, Cell Biology, 3. Good health, Immunology, biology.protein, Original Article, lipids (amino acids, peptides, and proteins), Antibody, medicine.symptom, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e132103a3e7a1e1162f7c69a943cce15

المؤلفون: C. Andrew Boswell, Rong Deng, Maya Leabman, Daniela Bumbaca, David West, Henry Chiu, Cinthia V. Pastuskovas, Jacqueline McBride, Suhasini Iyer, Hartmut Koeppen, Kyra J. Cowan, Clarissa Johnson, Yan Xin

المصدر: mAbs. 8(3)

مصطلحات موضوعية: 0301 basic medicine, Biodistribution, medicine.drug_class, Antibodies, Neoplasm, Immunology, Drug Evaluation, Preclinical, CHO Cells, Pharmacology, Monoclonal antibody, Anti-PD-L1 Monoclonal Antibody, B7-H1 Antigen, 03 medical and health sciences, Mice, 0302 clinical medicine, Cricetulus, Pharmacokinetics, PD-L1, Cricetinae, medicine, Immunology and Allergy, Distribution (pharmacology), Animals, Humans, Neoplasm Metastasis, Mice, Inbred BALB C, biology, Chemistry, Antibodies, Monoclonal, Cell Cycle Checkpoints, Neoplasms, Experimental, Neoplasm Proteins, Macaca fascicularis, 030104 developmental biology, 030220 oncology & carcinogenesis, Pharmacodynamics, biology.protein, Female, Antibody, Reports

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de18ea078057ebff816f4341bf616f92
https://pubmed.ncbi.nlm.nih.gov/26918260