يعرض 1 - 20 نتائج من 245 نتيجة بحث عن '"Jennifer J. Linderman"', وقت الاستعلام: 0.68s تنقيح النتائج
  1. 1
    Academic Journal
    Characterizing heterogeneous single-cell dose responses computationally and experimentally using threshold inhibition surfaces and dose-titration assays

    المؤلفون: Patrick C. Kinnunen, Brock A. Humphries, Gary D. Luker, Kathryn E. Luker, Jennifer J. Linderman

    المصدر: npj Systems Biology and Applications, Vol 10, Iss 1, Pp 1-12 (2024)

    مصطلحات موضوعية: Biology (General), QH301-705.5

    وصف الملف: electronic resource

    Relation: https://doaj.org/toc/2056-7189

    URL الوصول: https://doaj.org/article/e9d2e1fcf43e45e48dc5c893a3cd6bb6

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  2. 2
    Academic Journal
    Integrating inverse reinforcement learning into data-driven mechanistic computational models: a novel paradigm to decode cancer cell heterogeneity

    المؤلفون: Patrick C. Kinnunen, Kenneth K. Y. Ho, Siddhartha Srivastava, Chengyang Huang, Wanggang Shen, Krishna Garikipati, Gary D. Luker, Nikola Banovic, Xun Huan, Jennifer J. Linderman, Kathryn E. Luker

    المصدر: Frontiers in Systems Biology, Vol 4 (2024)

    مصطلحات موضوعية: inverse reinforcment learning, mechanistic modeling, machine learning, cellular heterogeneity, live-cell microscopy, Physiology, QP1-981

    وصف الملف: electronic resource

    Relation: https://www.frontiersin.org/articles/10.3389/fsysb.2024.1333760/full; https://doaj.org/toc/2674-0702

    URL الوصول: https://doaj.org/article/be160e1e9e7845c4a5123e42183ab88b

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  3. 3
    Academic Journal
    A framework for multi-scale intervention modeling: virtual cohorts, virtual clinical trials, and model-to-model comparisons

    المؤلفون: Christian T. Michael, Sayed Ahmad Almohri, Jennifer J. Linderman, Denise E. Kirschner

    المصدر: Frontiers in Systems Biology, Vol 3 (2024)

    مصطلحات موضوعية: model study design, digital partners, disease modeling, tuberculosis, computational biology, pharmacokinetic-pharmacodynamic model, Physiology, QP1-981

    وصف الملف: electronic resource

    Relation: https://www.frontiersin.org/articles/10.3389/fsysb.2023.1283341/full; https://doaj.org/toc/2674-0702

    URL الوصول: https://doaj.org/article/86874475a14645c9a49b4ee563927aac

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  4. 4
    Academic Journal
    Concomitant immunity to M. tuberculosis infection

    المؤلفون: Louis R. Joslyn, JoAnne L. Flynn, Denise E. Kirschner, Jennifer J. Linderman

    المصدر: Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)

    مصطلحات موضوعية: Medicine, Science

    وصف الملف: electronic resource

    Relation: https://doaj.org/toc/2045-2322

    URL الوصول: https://doaj.org/article/2142c077147c49f5b7fe08c4bb5950db

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  5. 5
    Academic Journal
    Co-optimization of therapeutic antibody affinity and specificity using machine learning models that generalize to novel mutational space

    المؤلفون: Emily K. Makowski, Patrick C. Kinnunen, Jie Huang, Lina Wu, Matthew D. Smith, Tiexin Wang, Alec A. Desai, Craig N. Streu, Yulei Zhang, Jennifer M. Zupancic, John S. Schardt, Jennifer J. Linderman, Peter M. Tessier

    المصدر: Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)

    مصطلحات موضوعية: Science

    وصف الملف: electronic resource

    Relation: https://doaj.org/toc/2041-1723

    URL الوصول: https://doaj.org/article/0014043dced04499aebddc31d0764ef0

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  6. 6
    Academic Journal
    Space physics guide to STRIDE: Strategies and tactics for recruiting to improve diversity and excellence

    المؤلفون: Michael W. Liemohn, Jennifer J. Linderman, Isis H. Settles

    المصدر: Frontiers in Astronomy and Space Sciences, Vol 10 (2023)

    مصطلحات موضوعية: space physics, equity, DEI, NSF ADVANCE, hiring, demographics, Astronomy, QB1-991, Geophysics. Cosmic physics, QC801-809

    وصف الملف: electronic resource

    Relation: https://www.frontiersin.org/articles/10.3389/fspas.2023.1152567/full; https://doaj.org/toc/2296-987X

    URL الوصول: https://doaj.org/article/76fa1d6f29a74e7fb0dc02cfe103d752

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  7. 7
    Academic Journal
    A multi-scale pipeline linking drug transcriptomics with pharmacokinetics predicts in vivo interactions of tuberculosis drugs

    المؤلفون: Joseph M. Cicchese, Awanti Sambarey, Denise Kirschner, Jennifer J. Linderman, Sriram Chandrasekaran

    المصدر: Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)

    مصطلحات موضوعية: Medicine, Science

    وصف الملف: electronic resource

    Relation: https://doaj.org/toc/2045-2322

    URL الوصول: https://doaj.org/article/58251f8464314b818121f7cf9632b6a2

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  8. 8
    Academic Journal
    Corrigendum: Spatial Organization and Recruitment of Non-Specific T Cells May Limit T Cell-Macrophage Interactions Within Mycobacterium tuberculosis Granulomas

    المؤلفون: Jess A. Millar, J. Russell Butler, Stephanie Evans, Nicole L. Grant, Joshua T. Mattila, Jennifer J. Linderman, JoAnne L. Flynn, Denise E. Kirschner

    المصدر: Frontiers in Immunology, Vol 12 (2021)

    مصطلحات موضوعية: T cell, macrophage, Mycobacterium tuberculosis, lung, computational model, granuloma, Immunologic diseases. Allergy, RC581-607

    وصف الملف: electronic resource

    Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2021.790557/full; https://doaj.org/toc/1664-3224

    URL الوصول: https://doaj.org/article/bf3567b2577c4e5a9d254f761658596f

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  9. 9
    Academic Journal
    Neutrophil Dynamics Affect Mycobacterium tuberculosis Granuloma Outcomes and Dissemination

    المؤلفون: Caitlin Hult, Joshua T. Mattila, Hannah P. Gideon, Jennifer J. Linderman, Denise E. Kirschner

    المصدر: Frontiers in Immunology, Vol 12 (2021)

    مصطلحات موضوعية: tuberculosis (TB), dissemination, nonhuman primate (NHP), sensitivity analysis (SA), agent-based model (ABM), neutrophil, Immunologic diseases. Allergy, RC581-607

    وصف الملف: electronic resource

    Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2021.712457/full; https://doaj.org/toc/1664-3224

    URL الوصول: https://doaj.org/article/ffd382aa6ff94234b3091ff7cd878378

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  10. 10
    Academic Journal
    Spatial Organization and Recruitment of Non-Specific T Cells May Limit T Cell-Macrophage Interactions Within Mycobacterium tuberculosis Granulomas

    المؤلفون: Jess A. Millar, J. Russell Butler, Stephanie Evans, Nicole L. Grant, Joshua T. Mattila, Jennifer J. Linderman, JoAnne L. Flynn, Denise E. Kirschner

    المصدر: Frontiers in Immunology, Vol 11 (2021)

    مصطلحات موضوعية: T cell, macrophage, Mycobacterium tuberculosis, lung, computational model, granuloma, Immunologic diseases. Allergy, RC581-607

    وصف الملف: electronic resource

    Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2020.613638/full; https://doaj.org/toc/1664-3224

    URL الوصول: https://doaj.org/article/18bc1f958e4442d3b25681c8a9dfda80

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  11. 11
    Academic Journal
    Both Pharmacokinetic Variability and Granuloma Heterogeneity Impact the Ability of the First-Line Antibiotics to Sterilize Tuberculosis Granulomas

    المؤلفون: Joseph M. Cicchese, Véronique Dartois, Denise E. Kirschner, Jennifer J. Linderman

    المصدر: Frontiers in Pharmacology, Vol 11 (2020)

    مصطلحات موضوعية: agent-based model, pharmacokinetic/pharmacodynamic (PK/PD) model, multi-scale model, isoniazid, rifampin, tissue distribution, Therapeutics. Pharmacology, RM1-950

    وصف الملف: electronic resource

    Relation: https://www.frontiersin.org/article/10.3389/fphar.2020.00333/full; https://doaj.org/toc/1663-9812

    URL الوصول: https://doaj.org/article/acbad03bd7b94fb2af3327865b37c85f

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  12. 12
    Academic Journal
    Integrating Non-human Primate, Human, and Mathematical Studies to Determine the Influence of BCG Timing on H56 Vaccine Outcomes

    المؤلفون: Louis R. Joslyn, Elsje Pienaar, Robert M. DiFazio, Sara Suliman, Benjamin M. Kagina, JoAnne L. Flynn, Thomas J. Scriba, Jennifer J. Linderman, Denise E. Kirschner

    المصدر: Frontiers in Microbiology, Vol 9 (2018)

    مصطلحات موضوعية: tuberculosis, non-human primate, H56, mathematical modeling, bacillus calmette–guerin (BCG), vaccination, Microbiology, QR1-502

    وصف الملف: electronic resource

    Relation: https://www.frontiersin.org/article/10.3389/fmicb.2018.01734/full; https://doaj.org/toc/1664-302X

    URL الوصول: https://doaj.org/article/21bb1f183e814d17bd59eefb8efaf249

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  13. 13
    Academic Journal
    A population model capturing dynamics of tuberculosis granulomas predicts host infection outcomes

    المؤلفون: Chang Gong, Jennifer J. Linderman, Denise Kirschner

    المصدر: Mathematical Biosciences and Engineering, Vol 12, Iss 3, Pp 625-642 (2015)

    مصطلحات موضوعية: within-host model., tb, granuloma, ode model, infectious disease, Biotechnology, TP248.13-248.65, Mathematics, QA1-939

    وصف الملف: electronic resource

    Relation: https://doaj.org/toc/1551-0018

    URL الوصول: https://doaj.org/article/3d54a4a55a10457dbf7096b4042cdd76

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  14. 14
    Academic Journal
    Deletion of TGF-β1 Increases Bacterial Clearance by Cytotoxic T Cells in a Tuberculosis Granuloma Model

    المؤلفون: Hayley C. Warsinske, Elsje Pienaar, Jennifer J. Linderman, Joshua T. Mattila, Denise E. Kirschner

    المصدر: Frontiers in Immunology, Vol 8 (2017)

    مصطلحات موضوعية: cells-T cells, cytotoxic, infections-bacterial, transforming growth factor beta, tuberculosis, pulmonary, Immunologic diseases. Allergy, RC581-607

    وصف الملف: electronic resource

    Relation: http://journal.frontiersin.org/article/10.3389/fimmu.2017.01843/full; https://doaj.org/toc/1664-3224

    URL الوصول: https://doaj.org/article/fe737494f83d4531bdb8df314ed6dd39

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  15. 15
    Academic Journal
    The Role of Dimensionality in Understanding Granuloma Formation

    المؤلفون: Simeone Marino, Caitlin Hult, Paul Wolberg, Jennifer J. Linderman, Denise E. Kirschner

    المصدر: Computation, Vol 6, Iss 4, p 58 (2018)

    مصطلحات موضوعية: 3D agent-based model, tuberculosis, granuloma, stochastic model calibration, 2D vs. 3D, Electronic computers. Computer science, QA75.5-76.95

    وصف الملف: electronic resource

    Relation: https://www.mdpi.com/2079-3197/6/4/58; https://doaj.org/toc/2079-3197

    URL الوصول: https://doaj.org/article/8026a23dd2004eb49b91fbe7d078346d

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  16. 16
    Academic Journal
    Quantification of Fibronectin Adsorption to Silicone-Rubber Cell Culture Substrates

    المؤلفون: James J. Cunningham, Janeta Nikolovski, Jennifer J. Linderman, David J. Mooney

    المصدر: BioTechniques, Vol 32, Iss 4, Pp 876-887 (2002)

    مصطلحات موضوعية: Biology (General), QH301-705.5

    وصف الملف: electronic resource

    Relation: https://doaj.org/toc/0736-6205; https://doaj.org/toc/1940-9818

    URL الوصول: https://doaj.org/article/83ec4e17234846ec903e2b5976640c95

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  17. 17
    Academic Journal
    NF-κB signaling dynamics play a key role in infection control in tuberculosis

    المؤلفون: Mohammad eFallahi-Sichani, Denise E. Kirschner, Jennifer J. Linderman

    المصدر: Frontiers in Physiology, Vol 3 (2012)

    مصطلحات موضوعية: Granuloma, Systems Biology, Tuberculosis, NF-κB signaling pathway, Tumor necrosis factor, Multi-scale modeling, Physiology, QP1-981

    وصف الملف: electronic resource

    Relation: http://journal.frontiersin.org/Journal/10.3389/fphys.2012.00170/full; https://doaj.org/toc/1664-042X

    URL الوصول: https://doaj.org/article/254479b1a6924d679f4ebe8e9c232471

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  18. 18
    Academic Journal
    Optimizing tuberculosis treatment efficacy: Comparing the standard regimen with Moxifloxacin-containing regimens.

    المؤلفون: Maral Budak, Joseph M Cicchese, Pauline Maiello, H Jacob Borish, Alexander G White, Harris B Chishti, Jaime Tomko, L James Frye, Daniel Fillmore, Kara Kracinovsky, Jennifer Sakal, Charles A Scanga, Philana Ling Lin, Véronique Dartois, Jennifer J Linderman, JoAnne L Flynn, Denise E Kirschner

    المصدر: PLoS Computational Biology, Vol 19, Iss 6, p e1010823 (2023)

    مصطلحات موضوعية: Biology (General), QH301-705.5

    Relation: https://doi.org/10.1371/journal.pcbi.1010823; https://doaj.org/toc/1553-734X; https://doaj.org/toc/1553-7358; https://doaj.org/article/6c3730d6ea76411e8f9be1bff53e7a93

    الاتاحة: https://doi.org/10.1371/journal.pcbi.1010823
    https://doaj.org/article/6c3730d6ea76411e8f9be1bff53e7a93

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  19. 19
    DataSheet1_A framework for multi-scale intervention modeling: virtual cohorts, virtual clinical trials, and model-to-model comparisons.DOCX

    المؤلفون: Christian T. Michael, Sayed Ahmad Almohri, Jennifer J. Linderman, Denise E. Kirschner

    مصطلحات موضوعية: Immunology, Systems Biology, Systems Physiology, Proteomics and Intermolecular Interactions (excl. Medical Proteomics), Genomics, model study design, digital partners, disease modeling, tuberculosis, computational biology, pharmacokinetic-pharmacodynamic model, sensitivity analysis, agent-based model

    Relation: https://figshare.com/articles/dataset/DataSheet1_A_framework_for_multi-scale_intervention_modeling_virtual_cohorts_virtual_clinical_trials_and_model-to-model_comparisons_DOCX/25038173

    الاتاحة: https://doi.org/10.3389/fsysb.2023.1283341.s001
    https://figshare.com/articles/dataset/DataSheet1_A_framework_for_multi-scale_intervention_modeling_virtual_cohorts_virtual_clinical_trials_and_model-to-model_comparisons_DOCX/25038173

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  20. 20
    Video2_A framework for multi-scale intervention modeling: virtual cohorts, virtual clinical trials, and model-to-model comparisons.AVI

    المؤلفون: Christian T. Michael, Sayed Ahmad Almohri, Jennifer J. Linderman, Denise E. Kirschner

    مصطلحات موضوعية: Immunology, Systems Biology, Systems Physiology, Proteomics and Intermolecular Interactions (excl. Medical Proteomics), Genomics, model study design, digital partners, disease modeling, tuberculosis, computational biology, pharmacokinetic-pharmacodynamic model, sensitivity analysis, agent-based model

    Relation: https://figshare.com/articles/media/Video2_A_framework_for_multi-scale_intervention_modeling_virtual_cohorts_virtual_clinical_trials_and_model-to-model_comparisons_AVI/25038182

    الاتاحة: https://doi.org/10.3389/fsysb.2023.1283341.s004
    https://figshare.com/articles/media/Video2_A_framework_for_multi-scale_intervention_modeling_virtual_cohorts_virtual_clinical_trials_and_model-to-model_comparisons_AVI/25038182

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