المؤلفون: Reddy Ranjith K. Sama, Claudia Fallini, Rodolfo Gatto, Jeanne E. McKeon, Yuyu Song, Melissa S. Rotunno, Saul Penaranda, Izrail Abdurakhmanov, John E. Landers, Gerardo Morfini, Scott T. Brady, Daryl A. Bosco

المصدر: Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2045-2322

URL الوصول: https://doaj.org/article/f67025a8d9b84438822ee997bac6b02a

المؤلفون: Daryl A. Bosco, Francesca Massi, Brittany R. Morgan, Eric J. Schmidt, Salome Funes, Antoine Jégou, Sivakumar Boopathy, Osman Bilsel, Lauren C. O’Connor, Jeanne E. McKeon

المساهمون: Institut Jacques Monod (IJM (UMR_7592)), Université de Paris (UP)-Centre National de la Recherche Scientifique (CNRS), Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP)

المصدر: Proc Natl Acad Sci U S A
Proceedings of the National Academy of Sciences
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2021, 118 (23), pp.e2024605118. ⟨10.1073/pnas.2024605118⟩

مصطلحات موضوعية: Protein Conformation, alpha-Helical, Mutant, Formins, Context (language use), [SDV.BC.BC]Life Sciences [q-bio]/Cellular Biology/Subcellular Processes [q-bio.SC], macromolecular substances, Polymerization, Profilins, 03 medical and health sciences, 0302 clinical medicine, Mutant protein, Profilin-1, Animals, Humans, [SDV.BBM.BC]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biochemistry [q-bio.BM], Proteostasis Deficiencies, Actin, 030304 developmental biology, Polyproline helix, 0303 health sciences, Multidisciplinary, [SDV.BBM.BS]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Structural Biology [q-bio.BM], biology, Chemistry, Amyotrophic Lateral Sclerosis, Neurodegenerative Diseases, Biological Sciences, Actins, Cell biology, Phenotype, Mutation, biology.protein, Mutant Proteins, Protein folding, 030217 neurology & neurosurgery, HeLa Cells

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::439ea8326d2e7709ba14eb274303e794
https://doi.org/10.1073/pnas.2024605118

المؤلفون: E Danielle Dean, Lydia M Mexas, Natalie L Cápiro, Jeanne E McKeon, Mahlon R DeLong, Kurt D Pennell, Jonathan A Doorn, Vin Tangpricha, Gary W Miller, Marian L Evatt

المصدر: PLoS ONE, Vol 7, Iss 7, p e39227 (2012)

مصطلحات موضوعية: Medicine, Science

Relation: http://europepmc.org/articles/PMC3388077?pdf=render; https://doaj.org/toc/1932-6203; https://doaj.org/article/4de7426d10e342cea54c7441f927f4d9

الاتاحة: https://doi.org/10.1371/journal.pone.0039227
https://doaj.org/article/4de7426d10e342cea54c7441f927f4d9

المؤلفون: Jeanne E. McKeon, Kristen E. Hokenson, Cristina Suarez, Sarah A. Kim, Scott D. Edmands, Jennifer A. Tyson, Emily E. Stackpole, Adam C. Hall, Laura L. Campbell, Hanna Sherrill

المصدر: Toxicology. 283:1-7

مصطلحات موضوعية: N-Methylaspartate, Cell Survival, Anesthetics, General, Nitrous Oxide, Pharmacology, Biology, Toxicology, Mice, In vivo, medicine, Animals, Ketamine, General anaesthetic, gamma-Aminobutyric Acid, Cerebral Cortex, Neurons, Isoflurane, L-Lactate Dehydrogenase, GABAA receptor, Glutamate receptor, Neurotoxicity, medicine.disease, Mice, Inbred C57BL, Animals, Newborn, Microscopy, Fluorescence, Anesthesia, NMDA receptor, Microtubule-Associated Proteins, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3f6e87ec53a511c3df75bba80266cbe
https://doi.org/10.1016/j.tox.2011.01.014

المؤلفون: Jeanne E. McKeon, Lian Li, Lih-Shen Chin, Di Sha

المصدر: Cellular and molecular life sciences : CMLS. 72(9)

مصطلحات موضوعية: Enzyme complex, Ubiquitin-Protein Ligases, Ubiquitin C-Terminal Hydrolase, Parkin, Article, Deubiquitinating enzyme, Cell Line, Cellular and Molecular Neuroscience, Mice, Ubiquitin, Lysosome, medicine, Autophagy, Animals, Humans, Protein Interaction Maps, Polyubiquitin, Molecular Biology, Pharmacology, Mice, Knockout, biology, Ubiquitination, Parkinson Disease, Cell Biology, Ubiquitin ligase, Cell biology, nervous system diseases, medicine.anatomical_structure, Mutation, Proteolysis, biology.protein, Molecular Medicine, Lysosomes, Ubiquitin Thiolesterase

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4473c2a65d8171489ee4f1be67c2b0af
https://pubmed.ncbi.nlm.nih.gov/25403879

المؤلفون: Owen M Peters, Gabriela Toro Cabrera, Helene Tran, Leonard Petrucelli, Christian Mueller, Robert H Brown Jr, Tania F Gendron, Jeanne E Mckeon, Jake Metterville, Alexandra Weiss, Nicholas Wightman, Johnny Salameh, Juhyun Kim, Huaming Sun, Kevin B Boylan, Dennis Dickson, Zachary Kennedy, Ziqiang Lin, Yong-Jie Zhang, Lillian Daughrity, Chris Jung, Fen-Biao Gao, Peter C Sapp, H Robert Horvitz, Daryl A Bosco, Solange P Brown, Pieter De Jong

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://web.mit.edu/horvitz/www/assets/publications/peters2015.pdf.

وصف الملف: application/pdf

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1039.8796; http://web.mit.edu/horvitz/www/assets/publications/peters2015.pdf

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1039.8796
http://web.mit.edu/horvitz/www/assets/publications/peters2015.pdf

المؤلفون: Tania F. Gendron, Zachary Kennedy, Nicholas Wightman, Jake Metterville, Chris J. Jung, Juhyun Kim, Christian Mueller, Dennis W. Dickson, Kevin B. Boylan, Lillian M. Daughrity, Alexandra Weiss, Gabriela Toro Cabrera, Solange P. Brown, Johnny Salameh, Owen M. Peters, Huaming Sun, Helene Tran, Pieter J. de Jong, Robert H. Brown, Jeanne E. McKeon, Fen-Biao Gao, Leonard Petrucelli, Daryl A. Bosco, H. Robert Horvitz, Yong Jie Zhang, Peter C. Sapp, Ziqiang Lin

المساهمون: Massachusetts Institute of Technology. Department of Biology, McGovern Institute for Brain Research at MIT, Sapp, Peter C, Horvitz, Howard Robert

المصدر: PMC

مصطلحات موضوعية: Chromosomes, Artificial, Bacterial, Genotype, Transgene, Neuroscience(all), C9ORF72, Mice, Transgenic, Nerve Tissue Proteins, Biology, In Vitro Techniques, transgenic mice, Article, Exon, C9orf72, RAN translation, medicine, Animals, Humans, Amyotrophic lateral sclerosis (ALS), Cells, Cultured, Genetics, Cerebral Cortex, Neurons, DNA Repeat Expansion, C9orf72 Protein, microRNA, General Neuroscience, Neurodegeneration, Amyotrophic Lateral Sclerosis, RNA foci, Age Factors, frontotemporal dementia (FTD), neurodegeneration, RNA, Brain, Proteins, Dipeptides, medicine.disease, Molecular biology, 3. Good health, Disease Models, Animal, MicroRNAs, Gene Expression Regulation, repeat expansions, Frontotemporal Dementia, Trinucleotide repeat expansion

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67850a51cfbb578720443a75b0a99709