المؤلفون: Rienk Offringa, Catherine Olesch, Frederik Cichon, Mareike Grees, Norbert Schmees, Ulrike Roehn, Florian Prinz, Detlef Stoeckigt, Michael Erkelenz, Thi Thanh Uyen Nguyen, Ulf Boemer, Judith Günther, Marc Kunze, Kirstin Petersen, Dennis Kirchhoff

المصدر: Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)

مصطلحات موضوعية: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2051-1426

URL الوصول: https://doaj.org/article/07ab2b5c8fd7488eb234fe061e205932

المؤلفون: Rienk Offringa, Ralf Lesche, Iris Oezen, Michael Platten, Daniel Baumann, Christiane A Opitz, Ahmed Sadik, Catherine Olesch, Frederik Cichon, Norbert Schmees, Ulrike Roehn, Florian Prinz, Detlef Stoeckigt, Katharina Sahm, Nirmeen Elmadany, Christina Kober, Julian Roewe, Lars Roese, Benjamin Bader, Mátyás Gorjánácz, Helge Gottfried Roider, Gabriele Leder, Horst Irlbacher, Julien Lefranc, Mine Oezcan-Wahlbrink, Ankita Sati Batra, Rafael Carretero, Hilmar Weinmann, Ingo V Hartung, Bertolt Kreft, Ilona Gutcher

المصدر: Journal for ImmunoTherapy of Cancer, Vol 11, Iss 11 (2023)

مصطلحات موضوعية: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: https://jitc.bmj.com/content/11/11/e007495.full; https://doaj.org/toc/2051-1426

URL الوصول: https://doaj.org/article/bc1e59d7b2b148a6869f255df5b9d454

المؤلفون: Lilia Falkenstern, Victoria Georgi, Stefanie Bunse, Volker Badock, Manfred Husemann, Ulrike Roehn, Timo Stellfeld, Mark Fitzgerald, Steven Ferrara, Detlef Stöckigt, Carlo Stresemann, Ingo V. Hartung, Amaury Fernández-Montalván

المصدر: Scientific Reports, Vol 14, Iss 1, Pp 1-21 (2024)

مصطلحات موضوعية: Medicine, Science

Relation: https://doi.org/10.1038/s41598-023-50964-x; https://doaj.org/toc/2045-2322; https://doaj.org/article/86f7032f806147479748eda7c74b8341

الاتاحة: https://doi.org/10.1038/s41598-023-50964-x
https://doaj.org/article/86f7032f806147479748eda7c74b8341

المؤلفون: Karl Ziegelbauer, Dominik Mumberg, Michael Brands, Franz von Nussbaum, Bertolt Kreft, Martin Michels, Oliver von Ahsen, Anna-Lena Frisk, Marian Raschke, Stefan Prechtl, Benjamin Bader, Philip Lienau, Roland Neuhaus, Detlef Stoeckigt, Ulrich Klar, Dirk Kosemund, Volker Schulze, Marcus Koppitz, Gerhard Siemeister, Antje M. Wengner

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf0b68fc1d8f214b0b3e08ca88297410
https://doi.org/10.1158/1535-7163.22508437.v1

المؤلفون: Karl Ziegelbauer, Dominik Mumberg, Michael Brands, Franz von Nussbaum, Bertolt Kreft, Martin Michels, Oliver von Ahsen, Anna-Lena Frisk, Marian Raschke, Stefan Prechtl, Benjamin Bader, Philip Lienau, Roland Neuhaus, Detlef Stoeckigt, Ulrich Klar, Dirk Kosemund, Volker Schulze, Marcus Koppitz, Gerhard Siemeister, Antje M. Wengner

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2921d9472516e80123b05471c837506f
https://doi.org/10.1158/1535-7163.22508449.v1

المؤلفون: Karl Ziegelbauer, Dominik Mumberg, Michael Brands, Franz von Nussbaum, Bertolt Kreft, Martin Michels, Oliver von Ahsen, Anna-Lena Frisk, Marian Raschke, Stefan Prechtl, Benjamin Bader, Philip Lienau, Roland Neuhaus, Detlef Stoeckigt, Ulrich Klar, Dirk Kosemund, Volker Schulze, Marcus Koppitz, Gerhard Siemeister, Antje M. Wengner

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e9c126cf3b030f5383bcf8d4111e2f2
https://doi.org/10.1158/1535-7163.22508446.v1

المؤلفون: Karl Ziegelbauer, Dominik Mumberg, Michael Brands, Franz von Nussbaum, Bertolt Kreft, Martin Michels, Oliver von Ahsen, Anna-Lena Frisk, Marian Raschke, Stefan Prechtl, Benjamin Bader, Philip Lienau, Roland Neuhaus, Detlef Stoeckigt, Ulrich Klar, Dirk Kosemund, Volker Schulze, Marcus Koppitz, Gerhard Siemeister, Antje M. Wengner

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::471af036b499cdbb44ed74a80af4d2c5
https://doi.org/10.1158/1535-7163.22508434.v1

المؤلفون: Karl Ziegelbauer, Dominik Mumberg, Michael Brands, Franz von Nussbaum, Bertolt Kreft, Martin Michels, Oliver von Ahsen, Anna-Lena Frisk, Marian Raschke, Stefan Prechtl, Benjamin Bader, Philip Lienau, Roland Neuhaus, Detlef Stoeckigt, Ulrich Klar, Dirk Kosemund, Volker Schulze, Marcus Koppitz, Gerhard Siemeister, Antje M. Wengner

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ab6e5c8aa529b99980fb121751c20dc
https://doi.org/10.1158/1535-7163.22508443.v1

المؤلفون: Ingo Hartung, Masoud Vedadi, Magda Szewczyk, Volker Badock, Carlo Stresemann, Holger Steuber, Dalia Barsyte-Lovejoy, Shawna Organ, Norbert Schmees, Clara D. Christ, Detlef Stoeckigt, Steven Kennedy, Stefan Gradl, Cheryl H. Arrowsmith, Megha Abbey, Stephan Siegel, Andrea Haegebarth, Manfred Husemann, Fengling Li, Marcus Bauser, Joerg Weiske, Irene Chau, Viacheslav V. Trush, Peter Brown

المصدر: SLAS Discovery. 26:947-960

مصطلحات موضوعية: Models, Molecular, 0301 basic medicine, Thermal shift assay, High-throughput screening, Antineoplastic Agents, MAP3K2, Biochemistry, Analytical Chemistry, Small Molecule Libraries, Structure-Activity Relationship, 03 medical and health sciences, 0302 clinical medicine, Drug Discovery, Humans, Binding site, Protein kinase A, Kinase, Drug discovery, Chemistry, Hydrogen Bonding, Isothermal titration calorimetry, Histone-Lysine N-Methyltransferase, High-Throughput Screening Assays, 030104 developmental biology, 030220 oncology & carcinogenesis, Molecular Medicine, Hydrophobic and Hydrophilic Interactions, Protein Binding, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31088aa45c9fd48a4764afae98765927
https://doi.org/10.1177/24725552211019409

المؤلفون: Stefan Gradl (1947637), Holger Steuber (389496), Joerg Weiske (4532608), Magda M. Szewczyk (11020448), Norbert Schmees (9465651), Stephan Siegel (3989942), Detlef Stoeckigt (8549592), Clara D. Christ (2632918), Fengling Li (176389), Shawna Organ (129008), Megha Abbey (11020451), Steven Kennedy (1622182), Irene Chau (2276365), Viacheslav Trush (11020454), Dalia Barsyte-Lovejoy (1399687), Peter J. Brown (499896), Masoud Vedadi (210076), Cheryl Arrowsmith (196614), Manfred Husemann (11020457), Volker Badock (2632921), Marcus Bauser (1717309), Andrea Haegebarth (836207), Ingo V. Hartung (2281924), Carlo Stresemann (167880)

مصطلحات موضوعية: Pharmacology and Pharmaceutical Sciences not elsewhere classified, chemical probe, SMYD3, thermal shift assay, drug discovery

Relation: https://figshare.com/articles/journal_contribution/sj-pdf-1-jbx-10_1177_24725552211019409_Supplemental_material_for_Discovery_of_the_SMYD3_Inhibitor_BAY-6035_Using_Thermal_Shift_Assay_TSA_-Based_High-Throughput_Screening/14838602

الاتاحة: https://doi.org/10.25384/sage.14838602.v1

المؤلفون: Claudia Merz, Marcus Bauser, Martin Michels, Ashley Eheim, David T. Scadden, Henrik Seidel, Ralf Lesche, Timo Stellfeld, Hanna Meyer, Pascale Lejeune, Thomas Mueller, Detlef Stoeckigt, David B. Sykes, Steven James Ferrara, Sven Christian, Andrea Haegebarth, Judith Guenther, Andreas Janzer, Katja Zimmermann, Sherif El Sheikh, Stefan Gradl, Michael Bruening

المصدر: Cancer Research. 78:DDT02-04

مصطلحات موضوعية: 0301 basic medicine, Acute promyelocytic leukemia, Cancer Research, Acute leukemia, Myeloid, business.industry, Myeloid leukemia, Cancer, medicine.disease, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, medicine.anatomical_structure, Oncology, Differentiation therapy, 030220 oncology & carcinogenesis, Cancer research, Dihydroorotate dehydrogenase, medicine, Cytarabine, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::810e228e308047a51f2ef7b9122f3063
https://doi.org/10.1158/1538-7445.am2018-ddt02-04

المؤلفون: Julien Lefranc, Volker Klaus Schulze, Roman Christian Hillig, Hans Briem, Florian Prinz, Anne Mengel, Tobias Heinrich, Jozsef Balint, Srinivasan Rengachari, Horst Irlbacher, Detlef Stoeckigt, Ulf Boemer, Benjamin Bader, Stefan Nikolaus Gradl, Carl Friedrich Nising, Franz von Nussbaum, Dominik Mumberg, Daniel Panne, Antje Margret Wengner

مصطلحات موضوعية: Uncategorized, Science & Technology, Life Sciences & Biomedicine, Chemistry, Medicinal, Pharmacology & Pharmacy, IN-VIVO EFFICACY, BINDING KINASE 1, THERAPEUTIC TARGET, TBK1, POTENT, IDENTIFICATION, ACTIVATION, AUTOPHAGY, CANCERS, GENES

Relation: 2381/11955654.v1; https://figshare.com/articles/journal_contribution/Discovery_of_BAY-985_a_Highly_Selective_TBK1_IKK_epsilon_Inhibitor/11955654

الاتاحة: https://figshare.com/articles/journal_contribution/Discovery_of_BAY-985_a_Highly_Selective_TBK1_IKK_epsilon_Inhibitor/11955654

المؤلفون: Anders Friberg, Claudia Merz, Stefan Gradl, Marcus Bauser, David T. Scadden, Ashley Eheim, Henrik Seidel, Andrea Haegebarth, Hanna Meyer, Steven James Ferrara, Krzysztof Brzezinka, Pascale Lejeune, David B. Sykes, Julie-Aurore Losman, Katja Zimmermann, Laura Evans, Sven Christian, Detlef Stoeckigt, Andreas Janzer, Ralf Lesche

المصدر: Leukemia. 33(10)

مصطلحات موضوعية: 0301 basic medicine, Acute promyelocytic leukemia, Cancer Research, Oxidoreductases Acting on CH-CH Group Donors, Myeloid, THP-1 Cells, Retinoic acid, Dihydroorotate Dehydrogenase, Chromosomal translocation, Antineoplastic Agents, Apoptosis, HL-60 Cells, Mice, SCID, Translocation, Genetic, 03 medical and health sciences, chemistry.chemical_compound, Mice, 0302 clinical medicine, Leukemia, Promyelocytic, Acute, Mice, Inbred NOD, hemic and lymphatic diseases, Cell Line, Tumor, Medicine, Animals, Humans, THP1 cell line, Enzyme Inhibitors, neoplasms, business.industry, Myeloid leukemia, Cell Differentiation, Hematology, medicine.disease, Leukemia, Leukemia, Myeloid, Acute, 030104 developmental biology, medicine.anatomical_structure, Pyrimidines, Oncology, chemistry, 030220 oncology & carcinogenesis, Cancer research, Dihydroorotate dehydrogenase, Female, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb03783633912c9af747df44438ccf9c
https://pubmed.ncbi.nlm.nih.gov/30940908

المؤلفون: Steven Ferrara, Marcus Bauser, Katja Zimmermann, David T. Scadden, Ashley Eheim, Claudia Merz, David B. Sykes, Andreas Janzer, Andrea Haegebarth, Sven Christian, Hanna Meyer, Detlef Stoeckigt, Stefan Gradl

المصدر: Cancer Research. 79:3597-3597

مصطلحات موضوعية: Cancer Research, Myeloid, business.industry, Cell, Cancer, Germinal center, medicine.disease, Lymphoma, medicine.anatomical_structure, Oncology, hemic and lymphatic diseases, medicine, Dihydroorotate dehydrogenase, Cancer research, Stem cell, business, Diffuse large B-cell lymphoma

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::b903586d43fdaef391cad8692a0d0276
https://doi.org/10.1158/1538-7445.am2019-3597

المؤلفون: Benjamin Bader, Ilona Gutcher, Ludiwg Zorn, Lars Roese, Hilmar Weinmann, Christina Kober, Michael Platten, Ulrike Roehn, Bertolt Kreft, Iris Oezen, Horst Irlbacher, Detlef Stoeckigt, Rafael Carretero, Norbert Schmees, Ingo Hartung

المصدر: Cancer Research. 79:4454-4454

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Tumor microenvironment, biology, business.industry, medicine.medical_treatment, Immunosuppression, Aryl hydrocarbon receptor, Small molecule, In vitro, 03 medical and health sciences, chemistry.chemical_compound, 030104 developmental biology, 0302 clinical medicine, Oncology, chemistry, Tolerability, In vivo, 030220 oncology & carcinogenesis, biology.protein, Cancer research, Medicine, business, Kynurenine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::3b5018e1ced8aa35387f8677f5fb5b87
https://doi.org/10.1158/1538-7445.am2019-4454

المؤلفون: Katja Zimmermann, Henrik Seidel, Vera Puetter, Sherif El Sheikh, Steven James Ferrara, Stefan Gradl, Claudia Merz, Anders Friberg, Sven Christian, Andrea Haegebarth, Thomas Mueller, Ashley Eheim, Timo Stellfeld, David T. Scadden, Marcus Bauser, Duy Nguyen, Michael Niehues, Martina Schaefer, Michael Bruening, Martin Michels, Judith Guenther, Knut Eis, Detlef Stoeckigt, Hanna Meyer, Pascal Lejeune, Andreas Janzer, Han-Jie Zhou, David B. Sykes, Michael Kroeber

المصدر: Cancer Research. 79:2-2

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Myeloid, Phenotypic screening, Cancer, Biological activity, Biology, medicine.disease, 03 medical and health sciences, Leukemia, 030104 developmental biology, 0302 clinical medicine, medicine.anatomical_structure, Oncology, In vivo, 030220 oncology & carcinogenesis, medicine, Cancer research, Dihydroorotate dehydrogenase, Structure–activity relationship

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e6ee917949e8111944b8c7f5491d2229
https://doi.org/10.1158/1538-7445.am2019-2

المؤلفون: Julian Roewe, Horst Irlbacher, Florian Prinz, Mátyás Gorjánácz, Lars Roese, Ulrike Roehn, Bertolt Kreft, Norbert Schmees, Katharina Sahm, Michael Platten, Benjamin Bader, Hilmar Weinmann, Christina Kober, Rafael Carretero, Ingo Hartung, Iris Oezen, Ilona Gutcher, Detlef Stoeckigt

المصدر: Cancer Research. 79:1288-1288

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, biology, Chemistry, Monocyte, T cell, Dendritic cell, Aryl hydrocarbon receptor, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, medicine.anatomical_structure, Immune system, Oncology, 030220 oncology & carcinogenesis, biology.protein, medicine, Cancer research, Tumor necrosis factor alpha, Antibody, CD8

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::9eb4fa5d5c5885eaf1f788ce23b46a4b
https://doi.org/10.1158/1538-7445.am2019-1288

المؤلفون: Manfred Husemann, Fengling Li, Volker Badock, Viacheslav V. Trush, Detlef Stoeckigt, Cheryl H. Arrowsmith, Jörg Weiske, Shawna Organ, Stephan Siegel, Stefan Gradl, Amaury Ernesto Fernandez-Montalvan, Norbert Schmees, Magdalena M. Szewczyk, Holger Steuber, Masoud Vedadi, Steven Kennedy, Clara D. Christ, Marcus Bauser, Dalia Barsyte-Lovejoy, Andrea Haegebarth, Ingo Hartung, Carlo Stresemann, Peter Brown

المصدر: Cancer Research. 78:1646-1646

مصطلحات موضوعية: Cancer Research, Thermal shift assay, Methyltransferase, Oncology, Kinase, Chemistry, Transcriptional regulation, Methylation, MAP3K2, Binding site, Protein kinase A, Molecular biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::51143612007dd573d01cbe81426aa209
https://doi.org/10.1158/1538-7445.am2018-1646

المؤلفون: Ulrich Klar, Gerhard Siemeister, Bertolt Kreft, Volker Schulze, Dirk Kosemund, Michael Brands, Marian Raschke, Franz von Nussbaum, Dominik Mumberg, Karl Ziegelbauer, Oliver von Ahsen, Philip Lienau, Detlef Stoeckigt, Stefan Prechtl, Benjamin Bader, Martin Michels, Roland Neuhaus, Marcus Koppitz, Anna-Lena Frisk, Antje Margret Wengner

المصدر: Molecular cancer therapeutics. 15(4)

مصطلحات موضوعية: 0301 basic medicine, Male, Cancer Research, Drug Evaluation, Preclinical, Mitosis, Antineoplastic Agents, Cell Cycle Proteins, Pharmacology, Protein Serine-Threonine Kinases, 03 medical and health sciences, chemistry.chemical_compound, Mice, In vivo, Cell Line, Tumor, Antineoplastic Combined Chemotherapy Protocols, Drug Discovery, medicine, Animals, Humans, Kinase activity, Mode of action, Protein Kinase Inhibitors, Cell Proliferation, Chemistry, Kinase, Cancer, Protein-Tyrosine Kinases, medicine.disease, Xenograft Model Antitumor Assays, Rats, Tumor Burden, Enzyme Activation, Spindle checkpoint, Disease Models, Animal, 030104 developmental biology, Oncology, Paclitaxel, Female

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92168d57bbe4e445cd814b96f4fa0e8e
https://pubmed.ncbi.nlm.nih.gov/26832791

المؤلفون: Clara D. Christ, Roman C. Hillig, Bernard Haendler, Hilmar Weinmann, Anke Mueller-Fahrnow, Naomi Barak, Markus Berger, Erik Eggert, Carlo Stresemann, Masoud Vedadi, Antonius Ter Laak, Stephan Siegel, Cora Scholten, Oleg Fedorov, Andrea Haegebarth, Amaury Ernesto Fernandez-Montalvan, Ursula Egner, Simon H. Holton, Peter Brown, Joerg Weiske, Mátyás Gorjánácz, Volker Badock, Ingo Hartung, Seong Joo Koo, Timo Stellfeld, Susanne Mueller, Kilian Huber, Cheryl H. Arrowsmith, Detlef Stoeckigt

المصدر: Cancer Research. 77:5239-5239

مصطلحات موضوعية: Cancer Research, Methyltransferase, biology, Cancer, Epigenome, Histone acetyltransferase, Computational biology, medicine.disease, Bioinformatics, Bromodomain, Chromatin, Oncology, medicine, biology.protein, Epigenetics, Transcription factor

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::56594940be9cc1edaa3da3e7c254f327
https://doi.org/10.1158/1538-7445.am2017-5239