المؤلفون: Cassandra Kirk, Guangrong Zhang, Jon C. Mirsalis, John Coughlin, John D. Morrey, Brent E. Korba, Carol E. Green, Chandrika P. Govardhan, Radhakrishnan P. Iyer, Seetharamaiyer Padmanabhan, Kathleen O’Loughlin

المصدر: Bioorganic & Medicinal Chemistry Letters. 20:1783-1786

مصطلحات موضوعية: Male, Hepatitis B virus, Clinical Biochemistry, Administration, Oral, Pharmaceutical Science, Mice, Transgenic, Pharmacology, medicine.disease_cause, Antiviral Agents, Biochemistry, Article, Rats sprague dawley, Cell Line, Rats, Sprague-Dawley, Mice, Drug Discovery, medicine, Animals, Humans, Prodrugs, Molecular Biology, Anti hbv, Nucleotides, Chemistry, Organic Chemistry, virus diseases, Prodrug, Hepatitis B, medicine.disease, digestive system diseases, Rats, Mice transgenic, Bioavailability, stomatognathic diseases, Mutation, Molecular Medicine, Female

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b421b8657375e1896ab57d4eb3387c2
https://doi.org/10.1016/j.bmcl.2010.01.010

المؤلفون: Chandrika P. Govardhan, Robert H. Abeles

المصدر: Archives of Biochemistry and Biophysics. 280:137-146

مصطلحات موضوعية: Magnetic Resonance Spectroscopy, Serine Proteinase Inhibitors, Stereochemistry, medicine.medical_treatment, Molecular Sequence Data, Biophysics, Tripeptide, Biochemistry, Substrate Specificity, Structure-Activity Relationship, medicine, Humans, Protease Inhibitors, Amino Acid Sequence, Molecular Biology, Pancreatic elastase, chemistry.chemical_classification, Protease, Chymotrypsin, Pancreatic Elastase, Tetrapeptide, biology, Serine Endopeptidases, Elastase, Fluorine, Ketones, Kinetics, Enzyme, chemistry, Enzyme inhibitor, biology.protein, Leukocyte Elastase, Oligopeptides

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44d251e6ab2dba2c52186616d1ae4086
https://doi.org/10.1016/0003-9861(90)90528-7

المؤلفون: Chandrika P Govardhan

المصدر: Current opinion in biotechnology. 10(4)

مصطلحات موضوعية: chemistry.chemical_classification, Chemistry, Industrial catalysts, Biomedical Engineering, Bioengineering, Protein engineering, In Vitro Techniques, Protein Engineering, law.invention, Enzymes, Enzyme, Cross-Linking Reagents, Chemical engineering, law, Enzyme Stability, Organic chemistry, Crystallization, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcd65119be1ef83c64931c6798a23089
https://pubmed.ncbi.nlm.nih.gov/10449320

المؤلفون: Robert H. Abeles, Chandrika P. Govardhan

المصدر: Archives of biochemistry and biophysics. 330(1)

مصطلحات موضوعية: Proteases, Magnetic Resonance Spectroscopy, Double bond, Stereochemistry, Phenylalanine, Biophysics, Cysteine Proteinase Inhibitors, Biochemistry, Chloride, Cathepsin B, chemistry.chemical_compound, Structure-Activity Relationship, Nucleophile, Papain, medicine, Organic chemistry, Cysteine, Molecular Biology, chemistry.chemical_classification, Binding Sites, Molecular Structure, Chemistry, Kinetics, Enzyme, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f72344ff5e2323e0f44c82910e401716
https://pubmed.ncbi.nlm.nih.gov/8651683

المؤلفون: S. Pazhanisamy, Chandrika P. Govardhan, R. F. Pratt

المصدر: Biochemistry. 28:6863-6870

مصطلحات موضوعية: chemistry.chemical_classification, Reaction mechanism, Binding Sites, Chemistry, Stereochemistry, Kinetics, Enterobacter, Glycine, Peptide, Models, Theoretical, Biochemistry, beta-Lactamases, Substrate Specificity, Amino acid, Hydrolysis, chemistry.chemical_compound, Aminolysis, Enterobacteriaceae, Isomerism, Amine gas treating, Amino Acids, Mathematics, Phenylacetates, Benzoic acid

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d47d28816daaf625e3133d150b229ecc
https://doi.org/10.1021/bi00443a013

المؤلفون: R. F. Pratt, W.Stephen Faraci, Chandrika P. Govardhan

المصدر: Analytical Biochemistry. 144:204-206

مصطلحات موضوعية: Biophysics, Carboxypeptidases, Muramoylpentapeptide Carboxypeptidase, Biochemistry, Streptomyces, Esterase, beta-Lactamases, Substrate Specificity, chemistry.chemical_compound, Cell Wall, pH indicator, Molecular Biology, chemistry.chemical_classification, Depsipeptide, biology, Streptomycetaceae, Hydrolysis, Esterases, Cell Biology, biology.organism_classification, Carboxypeptidase, Enzyme, chemistry, biology.protein, Actinomycetales

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bef00b8ebb924087b6d6068511879f9
https://doi.org/10.1016/0003-2697(85)90106-x

المؤلفون: R. F. Pratt, Chandrika P. Govardhan

المصدر: Biochemistry. 26(12)

مصطلحات موضوعية: Staphylococcus aureus, Magnetic Resonance Spectroscopy, Stereochemistry, Kinetics, Enterobacter, Muramoylpentapeptide Carboxypeptidase, Biochemistry, beta-Lactamases, Substrate Specificity, Hydrolysis, chemistry.chemical_compound, Nucleophile, Bacillus cereus, Enterobacteriaceae, Serine, Organic chemistry, Benzoic acid, chemistry.chemical_classification, Depsipeptide, biology, Bicyclic molecule, Carboxypeptidase, Enzyme, chemistry, biology.protein, Indicators and Reagents, Peptides, Mathematics

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e464a16007ed1503db03c4309072d8c
https://pubmed.ncbi.nlm.nih.gov/3115289

المؤلفون: Chandrika P. Govardhan, R. F. Pratt

المصدر: Proceedings of the National Academy of Sciences of the United States of America. 81(5)

مصطلحات موضوعية: Staphylococcus aureus, Magnetic Resonance Spectroscopy, Stereochemistry, Acylation, Enterobacter, medicine.disease_cause, Mass Spectrometry, beta-Lactamases, Substrate Specificity, Hydrolysis, Nucleophile, Bacillus cereus, medicine, Escherichia coli, Organic chemistry, Depsipeptide, chemistry.chemical_classification, Oligopeptide, Multidisciplinary, Chemistry, Nuclear magnetic resonance spectroscopy, Amino acid, Oligopeptides, Research Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd213794dc19a78b6ca6fce13916f1bd
https://pubmed.ncbi.nlm.nih.gov/6424114