نتائج البحث - "Andreas Buckl"

1

Small molecule Son of Sevenless 1 (SOS1) inhibitors: a review of the patent literature

المؤلفون: Adrian Liam Gill, Severin K. Thompson, Alexander G. Dossetter, Edward Jolyon Griffen, Andreas Buckl

المصدر: Expert Opinion on Therapeutic Patents. 31:1189-1204

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9648525d6a3c3ff6258428abacf16fc
https://doi.org/10.1080/13543776.2021.1952984

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2

Abstract 1598: RM-046, a first-in-class, mutant-selective, and oral KRASQ61H(ON) inhibitor that drives tumor regression in preclinical models and validates KRASQ61H as a therapeutic target

المصدر: Cancer Research. 83:1598-1598

مصطلحات موضوعية: Cancer Research, Oncology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::5b4c8ac4c8666e1ef6d5a72a0c1f2d65
https://doi.org/10.1158/1538-7445.am2023-1598

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3

Abstract 1273: Discovery of a potent, selective, and orally bioavailable SOS1 inhibitor, RMC-023, an in vivo tool compound that blocks RAS activation via disruption of the RAS-SOS1 interaction

المصدر: Cancer Research. 81:1273-1273

مصطلحات موضوعية: Cancer Research, Oncology, Chemistry, SOS1, Pharmacology, Bioavailability

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::84529dd9e8d7b5ae744e473068a78025
https://doi.org/10.1158/1538-7445.am2021-1273

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4

Abstract 4878: RMC-4550, an allosteric inhibitor of SHP2: Synthesis, structure, and anti-tumor activity

المصدر: Cancer Research. 78:4878-4878

مصطلحات موضوعية: 0301 basic medicine, Scaffold protein, 030103 biophysics, Cancer Research, Kinase, Chemistry, Allosteric regulation, Phosphatase, Protein tyrosine phosphatase, Pharmacology, 03 medical and health sciences, Oncology, Signal transduction, Receptor, ADME

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::b9799dbbd6e549ae1405a9baa4fbc959
https://doi.org/10.1158/1538-7445.am2018-4878

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5

Abstract 4877: Allosteric inhibition of SHP2 variants containing cancer-associated activating mutations

المؤلفون: Adrian Liam Gill, Gert Kiss, Daphne Hsieh, Jacqueline Smith, Robert J. Nichols, Chris M. Semko, Naing Aay, Ashutosh S. Jogalekar, Mellem Kevin, Mae Saldajeno-Concar, David Wildes, Won Walter, Andreas Buckl, Christopher J. Schulze, Carlos Stahlhut, Jason Romero, Christos Tzitzilonis, Elena S. Koltun, Abby Marquez

المصدر: Cancer Research. 78:4877-4877

مصطلحات موضوعية: 0301 basic medicine, Scaffold protein, Cancer Research, biology, Chemistry, Allosteric regulation, Mutant, HEK 293 cells, Protein tyrosine phosphatase, Molecular biology, Receptor tyrosine kinase, PTPN11, 03 medical and health sciences, 030104 developmental biology, Oncology, biology.protein, Signal transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e7ded4958643dc44622b33737ce5fb4d
https://doi.org/10.1158/1538-7445.am2018-4877

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6

The Search for Tricyanomethane (Cyanoform)

المؤلفون: Georg Wuitschik, W. Bernd Schweizer, Yi Lin Wu, Jack D. Dunitz, Lynne B. McCusker, Dubravka Šišak, Andreas Buckl

المصدر: Chemistry - A European Journal. 16:7224-7230

مصطلحات موضوعية: chemistry.chemical_classification, Hydronium, Organic Chemistry, Inorganic chemistry, Salt (chemistry), Iminium, Sulfuric acid, Hydrochloric acid, General Chemistry, Tautomer, Catalysis, Cyanoform, chemistry.chemical_compound, chemistry, Powder diffraction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e861ab0c8c21b29bee40484570497fd5
https://doi.org/10.1002/chem.201000559

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7

Spirocyclic oxetanes: synthesis and properties

المؤلفون: Björn Wagner, Andreas Buckl, Erick M. Carreira, Thierry Godel, Klaus Müller, Isabelle Parrilla, Moritz Märki, Mark Rogers-Evans, Georg Wuitschik, Maurizio Bernasconi, Josef Schneider, André Alker, Holger Fischer, Franz Schuler, W. Bernd Schweizer

المصدر: Angewandte Chemie (International ed. in English). 47(24)

مصطلحات موضوعية: chemistry.chemical_compound, chemistry, Solubility, Cyclization, Ethers, Cyclic, Morpholine, Morpholines, Organic chemistry, General Chemistry, General Medicine, Oxetane, Catalysis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28c74a0001e25cfcc14db41e7b66b42d
https://pubmed.ncbi.nlm.nih.gov/18465828

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8

Innentitelbild: Spirocyclic Oxetanes: Synthesis and Properties (Angew. Chem. 24/2008)

المؤلفون: Erick M. Carreira, Thierry Godel, Mark Rogers-Evans, Moritz Märki, Isabelle Parrilla, Andreas Buckl, Franz Schuler, Josef Schneider, Björn Wagner, Georg Wuitschik, W. Bernd Schweizer, Klaus Müller, Holger Fischer, André Alker, Maurizio Bernasconi

المصدر: Angewandte Chemie. 120:4522-4522

مصطلحات موضوعية: General Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::b76295f4ee9fc325345efe3f91ed82ff
https://doi.org/10.1002/ange.200890111

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9

Inside Cover: Spirocyclic Oxetanes: Synthesis and Properties (Angew. Chem. Int. Ed. 24/2008)

المؤلفون: Franz Schuler, W. Bernd Schweizer, Andreas Buckl, Holger Fischer, Klaus Müller, Mark Rogers-Evans, Thierry Godel, Erick M. Carreira, Björn Wagner, Maurizio Bernasconi, Moritz Märki, André Alker, Josef Schneider, Isabelle Parrilla, Georg Wuitschik

المصدر: Angewandte Chemie International Edition. 47:4450-4450

مصطلحات موضوعية: chemistry.chemical_compound, chemistry, Morpholine, INT, Organic chemistry, Cover (algebra), General Chemistry, Catalysis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::65e5f97eba372b42291f54734a7b0019
https://doi.org/10.1002/anie.200890112

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