المؤلفون: Burak Kürsad Günhan, Sebastian Weber, Abdelkader Seroutou, Tim Friede

المصدر: BMC Medical Research Methodology, Vol 21, Iss 1, Pp 1-14 (2021)

مصطلحات موضوعية: Phase I dose-escalation trials, Multiple treatment schedules, PK models, Bayesian statistics, Medicine (General), R5-920

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1471-2288

URL الوصول: https://doaj.org/article/3ba3de22ca8b4b09b849def7df152e0f

المؤلفون: Kerry Lynn Reynolds, Philippe L. Bedard, Se-Hoon Lee, Chia-Chi Lin, Josep Tabernero, Maria Alsina, Ezra Cohen, José Baselga, George Blumenschein, Donna M. Graham, Ignacio Garrido-Laguna, Dejan Juric, Sunil Sharma, Ravi Salgia, Abdelkader Seroutou, Xianbin Tian, Rose Fernandez, Alex Morozov, Qing Sheng, Thiruvamoor Ramkumar, Angela Zubel, Yung-Jue Bang

المصدر: BMC Cancer, Vol 17, Iss 1, Pp 1-11 (2017)

مصطلحات موضوعية: Phase I, HER3, HER2, Monoclonal antibody, LJM716, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: http://link.springer.com/article/10.1186/s12885-017-3641-6; https://doaj.org/toc/1471-2407

URL الوصول: https://doaj.org/article/6a99ce44899c48d0b69a8d0fc67f0c5c

المؤلفون: Reinhard Dummer, Tim Demuth, Laure Moutouh-de Parseval, Darrin D. Stuart, Giordano Caponigro, Vassilios Aslanis, Abdelkader Seroutou, Daniela Michel, Carlos Gomez-Roca, Manuel Hidalgo, Matteo S. Carlino, Richard F. Kefford, Ana Arance, Ryan Sullivan, Yasuhide Yamada, Amit Mahipal, Ragini Kudchakar, Grant A. McArthur, Marta Nyakas, Caroline Robert, Jean-Pierre Delord

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e582a2e6528fa79c1c59d17f45ea091
https://doi.org/10.1158/1078-0432.22467995

المؤلفون: Reinhard Dummer, Tim Demuth, Laure Moutouh-de Parseval, Darrin D. Stuart, Giordano Caponigro, Vassilios Aslanis, Abdelkader Seroutou, Daniela Michel, Carlos Gomez-Roca, Manuel Hidalgo, Matteo S. Carlino, Richard F. Kefford, Ana Arance, Ryan Sullivan, Yasuhide Yamada, Amit Mahipal, Ragini Kudchakar, Grant A. McArthur, Marta Nyakas, Caroline Robert, Jean-Pierre Delord

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e51957f9f54ec77b6c8a756ef60a095
https://doi.org/10.1158/1078-0432.22467989

المؤلفون: Reinhard Dummer, Tim Demuth, Laure Moutouh-de Parseval, Darrin D. Stuart, Giordano Caponigro, Vassilios Aslanis, Abdelkader Seroutou, Daniela Michel, Carlos Gomez-Roca, Manuel Hidalgo, Matteo S. Carlino, Richard F. Kefford, Ana Arance, Ryan Sullivan, Yasuhide Yamada, Amit Mahipal, Ragini Kudchakar, Grant A. McArthur, Marta Nyakas, Caroline Robert, Jean-Pierre Delord

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d33fd78b0f824a6d521ad7699f44e3c
https://doi.org/10.1158/1078-0432.c.6526808

المؤلفون: Nicole Gerwin, Celeste Scotti, Christine Halleux, Mara Fornaro, Jimmy Elliott, Yunyu Zhang, Kristen Johnson, Jian Shi, Sandra Walter, Yufei Li, Carsten Jacobi, Nelly Laplanche, Magali Belaud, Jochen Paul, Gustavo Glowacki, Thomas Peters, Keith A. Wharton, Igor Vostiar, Florine Polus, Ina Kramer, Sabine Guth, Abdelkader Seroutou, Subhajit Choudhury, Didier Laurent, Joseph Gimbel, Jörg Goldhahn, Matthias Schieker, Sophie Brachat, Ronenn Roubenoff, Michaela Kneissel

المصدر: Nature medicine. 28(12)

مصطلحات موضوعية: General Medicine, General Biochemistry, Genetics and Molecular Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f078387a12de39fc637fdf38fb32ac7
https://pubmed.ncbi.nlm.nih.gov/36456835

المؤلفون: Burak Kürsad, Günhan, Sebastian, Weber, Abdelkader, Seroutou, Tim, Friede

المصدر: BMC Medical Research Methodology, Vol 21, Iss 1, Pp 1-14 (2021)
BMC Medical Research Methodology

مصطلحات موضوعية: Medicine (General), Dose-Response Relationship, Drug, Maximum Tolerated Dose, Phase I dose-escalation trials, PK models, Bayes Theorem, Medical Oncology, Bayesian statistics, R5-920, Research Design, Neoplasms, Humans, Computer Simulation, Research Article, Multiple treatment schedules

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::1c7007fe74835ab7cc26fdb2a083864f
http://resolver.sub.uni-goettingen.de/purl?gs-1/17760

المؤلفون: Mounir Aout, Abdelkader Seroutou

المصدر: Open Journal of Statistics. :603-613

مصطلحات موضوعية: Oncology, medicine.medical_specialty, Safety profile, business.industry, Internal medicine, Maximum tolerated dose, Toxicity, Dose escalation, Medicine, Bayesian framework, business, Logistic regression, Bayesian logistic regression

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::517d1b3bc8f3e8e4487f826631e790a9
https://doi.org/10.4236/ojs.2018.83039

المؤلفون: Marta Nyakas, Grant A. McArthur, Giordano Caponigro, Daniela Michel, Ana Arance, Amit Mahipal, Tim Demuth, Ragini Kudchakar, Vassilios Aslanis, Caroline Robert, Matteo S. Carlino, Yasuhide Yamada, Richard F. Kefford, Manuel Hidalgo, Carlos Gomez-Roca, Ryan J. Sullivan, Abdelkader Seroutou, Laure Moutouh-de Parseval, Darrin Stuart, Jean Pierre Delord, Reinhard Dummer

المصدر: Clinical Cancer Research. 23:5339-5348

مصطلحات موضوعية: 0301 basic medicine, Oncology, Cancer Research, medicine.medical_specialty, Pharmacology, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Internal medicine, medicine, Kinase activity, Vemurafenib, Adverse effect, business.industry, Melanoma, Cancer, Dabrafenib, Binimetinib, medicine.disease, 030104 developmental biology, chemistry, Tolerability, 030220 oncology & carcinogenesis, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::17971a46f0b1b8343178177c031f98a8
https://doi.org/10.1158/1078-0432.ccr-16-2923

المؤلفون: Elena Elez, Martin Schuler, Helen Evans, Filip Janku, Gopa Iyer, Anastasios Stathis, Abdelkader Seroutou, Noboru Yamamoto, A. Mais, Daniel Shao-Weng Tan, Uz M. Stammberger

المصدر: Journal of Clinical Oncology. 38:3640-3640

مصطلحات موضوعية: MAPK/ERK pathway, Cancer Research, business.industry, Medizin, Small molecule, 03 medical and health sciences, Dose finding, 0302 clinical medicine, Oncology, 030220 oncology & carcinogenesis, Cancer cell, Cancer research, Medicine, In patient, business, 030215 immunology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c2031df4064b9e32cc29e94e54946dc
https://doi.org/10.1200/jco.2020.38.15_suppl.3640

المؤلفون: Burak Kürsad Günhan, Sebastian Weber, Abdelkader Seroutou, Tim Friede

مصطلحات موضوعية: FOS: Computer and information sciences, Applications (stat.AP), Statistics - Applications

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef6ff72194dd2e1ca36038ec35a45d73

المؤلفون: Se-Hoon Lee, Yung-Jue Bang, Qing Sheng, Thiruvamoor Ramkumar, Xianbin Tian, Maria Alsina, Abdelkader Seroutou, Rose Fernandez, Sunil Sharma, Kerry L. Reynolds, Philippe L. Bedard, Josep Tabernero, Donna M. Graham, Alex Morozov, Chia-Chi Lin, Dejan Juric, Angela Zubel, Ignacio Garrido-Laguna, José Baselga, George R. Blumenschein, Ezra E.W. Cohen, Ravi Salgia

المصدر: Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
BMC Cancer
BMC cancer, vol 17, iss 1
BMC Cancer, Vol 17, Iss 1, Pp 1-11 (2017)

مصطلحات موضوعية: 0301 basic medicine, Oncology, Male, Cancer Research, Esophageal Neoplasms, Receptor, ErbB-3, Receptor, ErbB-2, medicine.medical_treatment, LJM716, Targeted therapy, 0302 clinical medicine, ErbB-2, Antineoplastic Agents, Immunological, Surgical oncology, ErbB-3, 6.2 Cellular and gene therapies, Cancer, Middle Aged, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Metastatic breast cancer, 3. Good health, medicine.anatomical_structure, Immunological, Tolerability, Head and Neck Neoplasms, 030220 oncology & carcinogenesis, 6.1 Pharmaceuticals, Public Health and Health Services, Carcinoma, Squamous Cell, Female, Drug, Receptor, Research Article, Adult, Monoclonal antibody, medicine.medical_specialty, Maximum Tolerated Dose, Clinical Trials and Supportive Activities, Oncology and Carcinogenesis, Antineoplastic Agents, Breast Neoplasms, lcsh:RC254-282, Dose-Response Relationship, 03 medical and health sciences, Rare Diseases, Phase I, Pharmacokinetics, Clinical Research, Stomach Neoplasms, HER3, Internal medicine, HER2, Breast Cancer, Genetics, medicine, Humans, Oncology & Carcinogenesis, Esophagus, Aged, Dose-Response Relationship, Drug, business.industry, Squamous Cell Carcinoma of Head and Neck, Carcinoma, Evaluation of treatments and therapeutic interventions, Bayes Theorem, medicine.disease, 030104 developmental biology, Squamous Cell, Pharmacodynamics, business

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e9ba3f00e62b574ab3ea254c926c7a9
https://ddd.uab.cat/record/186327

المؤلفون: Jean-Pierre, Delord, Caroline, Robert, Marta, Nyakas, Grant A, McArthur, Ragini, Kudchakar, Amit, Mahipal, Yasuhide, Yamada, Ryan, Sullivan, Ana, Arance, Richard F, Kefford, Matteo S, Carlino, Manuel, Hidalgo, Carlos, Gomez-Roca, Daniela, Michel, Abdelkader, Seroutou, Vassilios, Aslanis, Giordano, Caponigro, Darrin D, Stuart, Laure, Moutouh-de Parseval, Tim, Demuth, Reinhard, Dummer

المصدر: Clinical cancer research : an official journal of the American Association for Cancer Research. 23(18)

مصطلحات موضوعية: Male, Proto-Oncogene Proteins B-raf, Sulfonamides, Maximum Tolerated Dose, Drug Evaluation, Preclinical, Antineoplastic Agents, Kaplan-Meier Estimate, Xenograft Model Antitumor Assays, Disease Models, Animal, Mice, Treatment Outcome, Mutation, Animals, Humans, Female, Carbamates, Molecular Targeted Therapy, Drug Monitoring, Melanoma, Protein Kinase Inhibitors, Neoplasm Staging

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::ea3ef1572b07e49ae0706239b6398ade
https://pubmed.ncbi.nlm.nih.gov/28611198

المؤلفون: Abdelkader Seroutou, Yan Ji, Marios Giannakis, Margaret E. McLaughlin, David Smith, Elena Garralda, Filip Janku, Jennifer Morawiak, Ulka N. Vaishampayan, Roisin M. Connolly, Jason R. Dobson, Sinead Dolan, Guillem Argiles, Jordi Rodon, Susan Moody, Maja J.A. de Jonge

المصدر: Cancer Research. 78:CT175-CT175

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Colorectal cancer, business.industry, Melanoma, Wnt signaling pathway, Cancer, medicine.disease, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Breast cancer, Oncology, 030220 oncology & carcinogenesis, Pancreatic cancer, Cancer research, medicine, AXIN2, business, Triple-negative breast cancer

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::80b7f4de129bb5703002843748ef0347
https://doi.org/10.1158/1538-7445.am2018-ct175

المؤلفون: Manuel Hidalgo, J. Tabernero, R. von Moos, Ana Arance, J.-P. Delord, Daniela Michel, Elena Elez, C. Robert, Carlos Gomez-Roca, Tim Demuth, Abdelkader Seroutou

المصدر: Annals of Oncology. 25:iv182

مصطلحات موضوعية: myalgia, education.field_of_study, medicine.medical_specialty, Colorectal cancer, business.industry, Population, Hematology, medicine.disease, Gastroenterology, Surgery, Oncology, Response Evaluation Criteria in Solid Tumors, Internal medicine, medicine, Progression-free survival, medicine.symptom, education, business, Vemurafenib, Adverse effect, Progressive disease, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::b30302c543f1fa3175aae988f10eeda7
https://doi.org/10.1093/annonc/mdu333.38

المؤلفون: Reynolds, Kerry, Bedard, Philippe, Se-Hoon Lee, Lin, Chia-Chi, Tabernero, Josep, Alsina, Maria, Cohen, Ezra, JosĂŠ Baselga, Blumenschein, George, Graham, Donna, Garrido-Laguna, Ignacio, Juric, Dejan, Sharma, Sunil, Salgia, Ravi, Abdelkader Seroutou, Xianbin Tian, Fernandez, Rose, Morozov, Alex, Sheng, Qing, Thiruvamoor Ramkumar, Zubel, Angela, Yung-Jue Bang

مصطلحات موضوعية: 3. Good health

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::58cd0cb335e6e362977b92d4d9a1aaf7

المؤلفون: Reynolds, Kerry, Bedard, Philippe, Se-Hoon Lee, Lin, Chia-Chi, Tabernero, Josep, Alsina, Maria, Cohen, Ezra, Baselga, José, Blumenschein, George, Graham, Donna, Garrido-Laguna, Ignacio, Juric, Dejan, Sharma, Sunil, Salgia, Ravi, Abdelkader Seroutou, Xianbin Tian, Fernandez, Rose, Morozov, Alex, Sheng, Qing, Thiruvamoor Ramkumar, Zubel, Angela, Yung-Jue Bang

مصطلحات موضوعية: 3. Good health

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::ed730898e43b1dfcc5f4172388f93fdb

المؤلفون: Reynolds, Kerry, Bedard, Philippe, Se-Hoon Lee, Lin, Chia-Chi, Tabernero, Josep, Alsina, Maria, Cohen, Ezra, JosĂŠ Baselga, Blumenschein, George, Graham, Donna, Garrido-Laguna, Ignacio, Juric, Dejan, Sharma, Sunil, Salgia, Ravi, Abdelkader Seroutou, Xianbin Tian, Fernandez, Rose, Morozov, Alex, Sheng, Qing, Thiruvamoor Ramkumar, Zubel, Angela, Yung-Jue Bang

مصطلحات موضوعية: neoplasms, 3. Good health

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::05ed0bbddcb1453058ced0582f809068

المؤلفون: Reynolds, Kerry, Bedard, Philippe, Se-Hoon Lee, Lin, Chia-Chi, Tabernero, Josep, Alsina, Maria, Cohen, Ezra, JosĂŠ Baselga, Blumenschein, George, Graham, Donna, Garrido-Laguna, Ignacio, Juric, Dejan, Sharma, Sunil, Salgia, Ravi, Abdelkader Seroutou, Xianbin Tian, Fernandez, Rose, Morozov, Alex, Sheng, Qing, Thiruvamoor Ramkumar, Zubel, Angela, Yung-Jue Bang

مصطلحات موضوعية: neoplasms, 3. Good health

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::dc359613384b22fead24097094f43330

المؤلفون: Reynolds, Kerry, Bedard, Philippe, Se-Hoon Lee, Lin, Chia-Chi, Tabernero, Josep, Alsina, Maria, Cohen, Ezra, Baselga, José, Blumenschein, George, Graham, Donna, Garrido-Laguna, Ignacio, Juric, Dejan, Sharma, Sunil, Salgia, Ravi, Abdelkader Seroutou, Xianbin Tian, Fernandez, Rose, Morozov, Alex, Sheng, Qing, Thiruvamoor Ramkumar, Zubel, Angela, Yung-Jue Bang

مصطلحات موضوعية: 3. Good health

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::ea1aa7f8a30ce0cc2c5c2a0460b79c0a